| Tag | Content |
|---|---|
| Uniprot ID | A0A2J8KRU7; H2RDB0; |
| Entrez ID | 453744 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_009429546.2; XM_009429547.2; |
| Ensembl protein ID | ENSPTRP00000058539 |
| Ensembl nucleotide ID | ENSPTRG00000007280 |
| Gene name | Cytochrome P450 family 1 subfamily A member 1 |
| Gene symbol | CYP1A1 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MLFPISMSAT EFLLASVIFC LVFWVIRASR PRVPKGLKNP PGPWGWPLIG HMLTLGKNPH 60 LALSRMSQQY GDVLQIRIGS TPVVVLSGLD TIRQALVRQG DDFKGRPDLY TFTLISNGQS 120 MSFSPDSGPV WAARRRLAQN GLKSFSIASD PASSTSCYLE EHVSKEAEVL ISTLQELMAG 180 PGHFNPYRYV VVSVTNVICA ICFGRRYDHN HQELLSLVNL NNNFGEVVGS GNPADFIPIL 240 RYLPNPSLNA FKDLNEKFYS FMQKMVKEHY KTFEKGHIRD ITDSLIEHCQ EKQLDENANV 300 QLSDEKIINI VLDLFGAGFD TVTTAISWSL MYLVMNPRVQ RKIQEELDTV IGRSRRPRLS 360 DRSHLPYMEA FILETFRHSS FVPFTIPHST TRDTSLKGFY IPKGRCVFVN QWQINHDQKL 420 WVNPSEFLPE RFLTPDGAID KVLSEKVIIF GMGKRKCIGE TIARWEVFLF LAILLQRVEF 480 SVPLGVKVDM TPIYGLTMKH ACCEHFQMQL RS 512 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | CYP1A1 | A0A452G3V1 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | CYP1A1 | 1543 | P04798 | CPO,CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Cyp1a1 | 13076 | P00184 | E12.4, E12.6, E12.5, E13.3, E12.8, E14.3 | Mus musculus | Prediction | More>> | |
| 1:1 ortholog | CYP1A1 | 453744 | A0A2J8KRU7 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | CYP1A1 | 403103 | Q8SQ69 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | CYP1A1 | 100328613 | P05176 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Cyp1a1 | 24296 | P00185 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0008391 | arachidonic acid monooxygenase activity |
| GO:0101020 | estrogen 16-alpha-hydroxylase activity |
| GO:0101021 | estrogen 2-hydroxylase activity |
| GO:0020037 | heme binding |
| GO:0005506 | iron ion binding |
| GO:0016712 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen |
| GO:0070576 | vitamin D 24-hydroxylase activity |
| GO:0009308 | amine metabolic process |
| GO:0071407 | cellular response to organic cyclic compound |
| GO:0008210 | estrogen metabolic process |
| GO:0006631 | fatty acid metabolic process |
| GO:0046483 | heterocycle metabolic process |
| GO:0050665 | hydrogen peroxide biosynthetic process |
| GO:0002933 | lipid hydroxylation |
| GO:0009636 | response to toxic substance |
| GO:0042572 | retinol metabolic process |
| GO:0009404 | toxin metabolic process |
| PROSITE ID | PROSITE Term |
|---|---|
| PS00086 | CYTOCHROME_P450 |
| Pfam ID | Pfam Term |
|---|---|
| PF00067 | p450 |