| Tag | Content |
|---|---|
| Uniprot ID | A0A452G3V1 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSCHIP00000031186 |
| Ensembl nucleotide ID | ENSCHIG00000025617 |
| Gene name | Uncharacterized protein |
| Gene symbol | CYP1A1 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MFSVFGLPIP ISATELLLAS AVFCLVFWVV RTWRPRVPQG LKSPPEPWGW PLLGHVLTLG 60 KNPHVVLSQL SQRYGDVLQI RIGYTPVLVL SGLDTIRQAL VRQGDDFKGR PDLYSFTLIT 120 EGQSMTFNPD SGPVWAARRR LAQNALKSFS TASDPASLSS CYLEEHVSKE AEYLLGKFQE 180 LMSGPGRFDP YRYVVVSVAN VICAMCFGRR YDHDDQEFLS LINLSNEFGE ITASGNPADF 240 IPVLRYLPNT ALDLFKDLNR RFYVFVQKIV KEHYKTFEKG HIRDITDSLI EHCQDKRLDE 300 NANIQLSDEK IINIVMDLFG AGFDTVTTAI SWSLLYLVTS PRVQKKIQEE VLKAGVAPDL 360 SGPLCSLSDR PQLPYLEAFI LETFRHSSFV PFTIPHSTTR DTNLNGFYIP KGRCVFVNQW 420 QINHDQKLWE DPSEFRPERF LTTDGTVNKV LSEKVIIFGL GKRKCIGEII ARLEVFLFLA 480 ILLHQVEFHV TPGVKVDMTP LYGLTMKHAR CEHFQVRMRS |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | CYP1A1 | A0A452G3V1 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | CYP1A1 | 1543 | P04798 | CPO,CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Cyp1a1 | 13076 | P00184 | E12.4, E12.6, E12.5, E13.3, E12.8, E14.3 | Mus musculus | Prediction | More>> | |
| 1:1 ortholog | CYP1A1 | 453744 | A0A2J8KRU7 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | CYP1A1 | 403103 | Q8SQ69 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | CYP1A1 | 100328613 | P05176 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Cyp1a1 | 24296 | P00185 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0008391 | arachidonic acid monooxygenase activity |
| GO:0101020 | estrogen 16-alpha-hydroxylase activity |
| GO:0101021 | estrogen 2-hydroxylase activity |
| GO:0020037 | heme binding |
| GO:0005506 | iron ion binding |
| GO:0016712 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen |
| GO:0070576 | vitamin D 24-hydroxylase activity |
| GO:0009308 | amine metabolic process |
| GO:0071407 | cellular response to organic cyclic compound |
| GO:0008210 | estrogen metabolic process |
| GO:0006631 | fatty acid metabolic process |
| GO:0046483 | heterocycle metabolic process |
| GO:0050665 | hydrogen peroxide biosynthetic process |
| GO:0002933 | lipid hydroxylation |
| GO:0009636 | response to toxic substance |
| GO:0042572 | retinol metabolic process |
| GO:0009404 | toxin metabolic process |
| PROSITE ID | PROSITE Term |
|---|---|
| PS00086 | CYTOCHROME_P450 |
| Pfam ID | Pfam Term |
|---|---|
| PF00067 | p450 |