| Tag | Content |
|---|---|
| Uniprot ID | Q8SQ69 |
| Entrez ID | 403103 |
| Genbank protein ID | AOC89038.1; HDA66558.1; AKO62671.1; BAB85660.1; |
| Genbank nucleotide ID | NM_214412.1 |
| Ensembl protein ID | |
| Ensembl nucleotide ID | |
| Gene name | Cytochrome P450 1A1 |
| Gene symbol | CYP1A1 |
| Organism | Sus scrofa |
| NCBI taxa ID | 9823 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MFSVFGLPIP ISATELLLAS AIFCLVFWVV RTWQPQVPKG LKSPPGPWGW PLLGHVLTLG 60 KSPHLALARL SQRYGDVLQI RIGCTPVLVL SGLDTIRQAL VRQGDDFKGR PDLYSFTLIS 120 NGQSMTFNPD SGPVWAARRR LAQKALNTFS IASDPASSSS CYLEDHVSKE AECLLGKFQE 180 LMAGPGHFDP YKYVLVSVAN VICAICFGQR YDHDNPELLS LINLSNEFGE VTAAGNPADF 240 IPILRYLPNT SLDLFKDLNQ KFYIFMQKMV REHYKIFEKG RIRDITDSLI EHCQDKRMDE 300 NANIQLSDEK IVNIVIDLFG AGFDTVTTAI SWSLMYLVTN PSIQRKIQEE LDTVIGQARR 360 PRLSDRPQLP YMEAFILELF RHTSFVPFTI PHSTTRDTSL NGFYIPKGRC VFVNQWQINH 420 DQKLWDDPSV FRPERFLTAD GTINKALGEK VILFGLGKRK CIGETIARLE VFLFLAILLQ 480 QVEFRVTPGV KVDMTPIYGL TMKHAHCEHV QMHVRS 516 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | CYP1A1 | A0A452G3V1 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | CYP1A1 | 1543 | P04798 | CPO,CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Cyp1a1 | 13076 | P00184 | E12.4, E12.6, E12.5, E13.3, E12.8, E14.3 | Mus musculus | Prediction | More>> | |
| 1:1 ortholog | CYP1A1 | 453744 | A0A2J8KRU7 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | CYP1A1 | 403103 | Q8SQ69 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | CYP1A1 | 100328613 | P05176 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Cyp1a1 | 24296 | P00185 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0008391 | arachidonic acid monooxygenase activity |
| GO:0101020 | estrogen 16-alpha-hydroxylase activity |
| GO:0101021 | estrogen 2-hydroxylase activity |
| GO:0020037 | heme binding |
| GO:0005506 | iron ion binding |
| GO:0016712 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen |
| GO:0070576 | vitamin D 24-hydroxylase activity |
| GO:0009308 | amine metabolic process |
| GO:0071407 | cellular response to organic cyclic compound |
| GO:0008210 | estrogen metabolic process |
| GO:0006631 | fatty acid metabolic process |
| GO:0046483 | heterocycle metabolic process |
| GO:0050665 | hydrogen peroxide biosynthetic process |
| GO:0002933 | lipid hydroxylation |
| GO:0009636 | response to toxic substance |
| GO:0042572 | retinol metabolic process |
| GO:0009404 | toxin metabolic process |
| PROSITE ID | PROSITE Term |
|---|---|
| PS00086 | CYTOCHROME_P450 |
| Pfam ID | Pfam Term |
|---|---|
| PF00067 | p450 |