| Tag | Content |
|---|---|
| Uniprot ID | A0A2J8MN19; H2Q1T1; |
| Entrez ID | 450396 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_016962976.1; XM_507735.5; |
| Ensembl protein ID | ENSPTRP00000004110 |
| Ensembl nucleotide ID | ENSPTRG00000002413 |
| Gene name | Integrin beta |
| Gene symbol | ITGB1 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MNLRPIFWIG LISSVCCVFA QTDENRCLKA NAKSCGECIQ AGPNCGWCTN STFLQEGMPT 60 SARCDDLEAL KKKGCPLDDI ENPRGSKDIK KNKNVTNRSK GTAEKLKPED ITQIQPQQLV 120 LRLRSGEPQT FTLKFKRAED YPIDLYYLMD LSYSMKDDLE NVKSLGTDLM NEMRRITSDF 180 RIGFGSFVEK TVMPYISTTP AKLRNPCTSE QNCTSPFSYK NVLSLTNKGE IFNELVGKQR 240 ISGNLDSPEG GFDAIMQVAV CGSLIGWRNV TRLLVFSTDA GFHFAGDGKL GGIVLPNDGQ 300 CHLENNMYTM SHYYDYPSIA HLVQKLSENN IQTIFAVTEE FQPVYKELKN LIPKSAVGTL 360 SANSSNVIQL IIDAYNSLSS EVILENGKLS EGVTISYKSY CKNGVNGTGE NGRKCSNISI 420 GDEVQFEISI TSNKCPKKDS DSFKIRPLGF TEEVEVILQY ICECECQSEG IPESPKCHEG 480 NGTFECGACR CNEGRVGRHC ECSTDEVNSE DMDAYCRKEN SSEICSNNGE CVCGQCVCRK 540 RDNTNEIYSG KFCECDNFNC DRSNGLICGG NGVCKCRVCE CNPNYTGSAC DCSLDTSTCE 600 ASNGQICNGR GICECGVCKC TDPKFQGQTC EMCQTCLGVC AEHKECVQCR AFNKGEKKDT 660 CTQECSYFNI TKVESRDKLP QPVQPDPVSH CKEKDVDDCW FYFTYSVNGN NEVMVHVVEN 720 PECPTGPDII PIVAGVVAGI VLIGLALLLI WKLLMIIHDR REFAKFEKEK MNAKWDTGEN 780 PIYKSAVTTV VNPKYEGK 798 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | ITGB1 | 102178060 | A0A452E668 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | ITGB1 | 3688 | P05556 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Itgb1 | 16412 | P09055 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | ITGB1 | 450396 | A0A2J8MN19 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | ITGB1 | 100008898 | A0A5F9C3C4 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Itgb1 | 24511 | A0A0G2JSK5 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0008305 | integrin complex |
| GO:0038023 | signaling receptor activity |
| GO:0007160 | cell-matrix adhesion |
| GO:0007229 | integrin-mediated signaling pathway |
| InterPro ID | InterPro Term |
|---|---|
| IPR013111 | EGF_extracell |
| IPR040622 | I-EGF_1 |
| IPR027071 | Integrin_beta-1 |
| IPR033760 | Integrin_beta_N |
| IPR015812 | Integrin_bsu |
| IPR014836 | Integrin_bsu_cyt_dom |
| IPR012896 | Integrin_bsu_tail |
| IPR036349 | Integrin_bsu_tail_dom_sf |
| IPR002369 | Integrin_bsu_VWA |
| IPR032695 | Integrin_dom_sf |
| IPR016201 | PSI |
| IPR036465 | vWFA_dom_sf |
| PROSITE ID | PROSITE Term |
|---|---|
| PS00243 | INTEGRIN_BETA |