| Tag | Content |
|---|---|
| Uniprot ID | A0A452E668 |
| Entrez ID | 102178060 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_018056845.1 |
| Ensembl protein ID | ENSCHIP00000007476 |
| Ensembl nucleotide ID | ENSCHIG00000010934 |
| Gene name | Integrin beta |
| Gene symbol | ITGB1 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MHLQLIFWIG LISSVCCVFG QADENRCLKA NAKSCGECIQ AGPNCGWCTN STFLQEGMPT 60 SARCDDLEAL KKKGCHPNDI ENPRGSKDIK KNKNVTNRSK GTAEKLQPED ITQIQPQQLV 120 LQLRSGEPQT FTLKFKRAED YPIDLYYLMD LSYSMKDDLE NVKSLGTDLM NEMRRITSDF 180 RIGFGSFVEK TVMPYISTTP AKLRNPCTNE QNCTSPFSYK NVLSLTDKGE VFNELVGKQR 240 ISGNLDSPEG GFDAIMQVAV CGSLIGWRNV TRLLVFSTDA GFHFAGDGKL GGIVLPNDGQ 300 CHLENDVYTM SHYYDYPSIA HLVQKLSENN IQTIFAVTEE FQPVYKELKN LIPKSAVGTL 360 SANSSNVIQL IIDAYNSLSS EVILENSKLP EGVTINYKSY CKNGVNGTGE NGRKCSNISI 420 GDEVQFEISI TANKCPNKNS ETIKIKPLGF TEEVEIILQF ICECECQSEG IPGSPKCHDG 480 NGTFECGACR CNEGRVGRHC ECSTDEVNSE DMDAYCRKEN SSEICSNNGE CVCGQCVCRK 540 RDNTNEIYSG KFCECDNFNC DRSNGLICGG NGVCKCRVCE CNPNYTGSAC DCSLDTTSCM 600 AVNGQICNGR GVCECGACKC TDPKFQGPTC EMCQTCLGVC AEHKECVQCR AFNKGEKKDT 660 CAQECSHFNI TKVENRDKLP QPGQVDPLSH CKEKDVDDCW FYFTYSVNGN NEATVHVVET 720 PECPTGPDII PIVAGVVAGI VLIGLALLLI WKLLMIIHDR REFAKFEKEK MNAKWDTGEN 780 PIYKSAVTTV VNPKYEGK 798 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | ITGB1 | 102178060 | A0A452E668 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | ITGB1 | 3688 | P05556 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Itgb1 | 16412 | P09055 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | ITGB1 | 450396 | A0A2J8MN19 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | ITGB1 | 100008898 | A0A5F9C3C4 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Itgb1 | 24511 | A0A0G2JSK5 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0008305 | integrin complex |
| GO:0038023 | signaling receptor activity |
| GO:0007160 | cell-matrix adhesion |
| GO:0007229 | integrin-mediated signaling pathway |
| InterPro ID | InterPro Term |
|---|---|
| IPR013111 | EGF_extracell |
| IPR040622 | I-EGF_1 |
| IPR027071 | Integrin_beta-1 |
| IPR033760 | Integrin_beta_N |
| IPR015812 | Integrin_bsu |
| IPR014836 | Integrin_bsu_cyt_dom |
| IPR012896 | Integrin_bsu_tail |
| IPR036349 | Integrin_bsu_tail_dom_sf |
| IPR002369 | Integrin_bsu_VWA |
| IPR032695 | Integrin_dom_sf |
| IPR016201 | PSI |
| IPR036465 | vWFA_dom_sf |
| PROSITE ID | PROSITE Term |
|---|---|
| PS00243 | INTEGRIN_BETA |