| Tag | Content |
|---|---|
| Uniprot ID | A0A5F9C3C4 |
| Entrez ID | 100008898 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_002721189.3 |
| Ensembl protein ID | ENSOCUP00000027559 |
| Ensembl nucleotide ID | ENSOCUG00000003623 |
| Gene name | Integrin beta |
| Gene symbol | ITGB1 |
| Organism | Oryctolagus cuniculus |
| NCBI taxa ID | 9986 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MNLQLIFWIG LLGSICCVFG QTDENRCLKA NAKSCGECIQ AGPNCGWCTN STFLQEGMPT 60 SARCDDLEAL KKKGCHPDDI ENPRGSRDIK KNKNVTNRSK GTAEKLQPED ITQIQPQQLV 120 LQLRSGEPQT FTLKFKRAED YPIDLYYLMD LSYSMKDDLE NVKSLGTDLM NEMRRVTSDF 180 RIGFGSFVEK TVMPYISTTP AKLKNPCTSE QNCTSPFSYK NVLSLTDRGE EFNELVGKQR 240 ISGNLDSPEG GFDAIMQVAV CGSLIGWRNV TRLLVFSTDA GFHFAGDGKL GGIVLPNDGQ 300 CHLEHNEYTM SHYYDYPSIA HLVQKLSENN IQTIFAVTEE FQPVYKELKN LIPKSAVGTL 360 SANSSNVIQL IIDAYNSLSS EVILENSKLP EGVTINYKSY CKNGVNGTGE NGRKCSNISI 420 GDEVHFEISI TSNQCPVKHS ETIKIKPLGF TEEVEVVLEF ICKCECQDTG IPRSPQCHDG 480 NGTFECGACR CNEGRVGRHC ECSTDEVNSE DMDAYCRKEN SSEICSNNGE CVCGQCVCRK 540 RDNTNEIYSG KFCECDNFNC DRSNGLICGG NGVCKCRVCE CNPNYTGSAC DCSLDTTSCM 600 ATNGQICNGR GICECGVCKC TDPKFQGQTC EMCQTCLGVC AEHKECVQCR AFNKGEKKDK 660 CAQECSHFNI TKVENRDKLP QPGQVDPLSH CKEKDVDDCW FYFTYSVNGN NEAIVHVVET 720 PECPTGPDII PIVAGVVAGI VLIGLALLLI WKLLMIIHDR REFAKFEKEK MNAKWDTGEN 780 PIYKSAVTTV VNPKYEGK 798 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | ITGB1 | 102178060 | A0A452E668 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | ITGB1 | 3688 | P05556 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Itgb1 | 16412 | P09055 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | ITGB1 | 450396 | A0A2J8MN19 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | ITGB1 | 100008898 | A0A5F9C3C4 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Itgb1 | 24511 | A0A0G2JSK5 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0008305 | integrin complex |
| GO:0038023 | signaling receptor activity |
| GO:0007160 | cell-matrix adhesion |
| GO:0007229 | integrin-mediated signaling pathway |
| InterPro ID | InterPro Term |
|---|---|
| IPR013111 | EGF_extracell |
| IPR040622 | I-EGF_1 |
| IPR027071 | Integrin_beta-1 |
| IPR033760 | Integrin_beta_N |
| IPR015812 | Integrin_bsu |
| IPR014836 | Integrin_bsu_cyt_dom |
| IPR012896 | Integrin_bsu_tail |
| IPR036349 | Integrin_bsu_tail_dom_sf |
| IPR002369 | Integrin_bsu_VWA |
| IPR032695 | Integrin_dom_sf |
| IPR016201 | PSI |
| IPR036465 | vWFA_dom_sf |
| PROSITE ID | PROSITE Term |
|---|---|
| PS00243 | INTEGRIN_BETA |