| Tag | Content |
|---|---|
| Uniprot ID | A0A452DM24 |
| Entrez ID | 102178704 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_018048111.1 |
| Ensembl protein ID | ENSCHIP00000000802 |
| Ensembl nucleotide ID | ENSCHIG00000000705 |
| Gene name | TGF_BETA_2 domain-containing protein |
| Gene symbol | GDF11 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MVLAAPLLLG FLLLALELRP RGEAAEGPAA AAAAAAAAAA GAGGERSSRP APSVAPEPDG 60 CPVCVWRQHS RELRLESIKS QILSKLRLKE APNISREVVK QLLPKAPPLQ QILDLHDFQG 120 DALQPEDFLE EDEYHATTET VISMAQETDP AVQTDGSPLC CHFHFSPKVM FTKVLKAQLW 180 VYLRPVPRPA TVYLQILRLK PLTGEGTAGG GGGGRRHIRI RSLKIDLHSR SGHWQSIDFK 240 QVLHSWFRQP QSNWGIEINA FDPSGTDLAV TSLGPGAEGL HPFMELRVLE NTKRSRRNLG 300 LDCDEHSSES RCCRYPLTVD FEAFGWDWII APKRYKANYC SGQCEYMFMQ KYPHTHLVQQ 360 ANPRGSAGPC CTPTKMSPIN MLYFNDKQQI IYGKIPGMVV DRCGCS 406 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | GDF11 | J9NYK9 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | GDF11 | 102178704 | A0A452DM24 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | GDF11 | 10220 | O95390 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Gdf11 | 14561 | Q9Z1W4 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | GDF11 | 451970 | H2Q663 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | GDF11 | F1SPJ6 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Gdf11 | 29454 | Q9Z217 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | gdf11 | 406247 | Q8JFP9 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005615 | extracellular space |
| GO:0005654 | nucleoplasm |
| GO:0032991 | protein-containing complex |
| GO:0008083 | growth factor activity |
| GO:0048593 | camera-type eye morphogenesis |
| GO:0048469 | cell maturation |
| GO:0001656 | metanephros development |
| GO:0045596 | negative regulation of cell differentiation |
| GO:0008285 | negative regulation of cell population proliferation |
| GO:0031016 | pancreas development |
| GO:0060021 | roof of mouth development |
| GO:0001501 | skeletal system development |
| GO:0060395 | SMAD protein signal transduction |
| GO:0021512 | spinal cord anterior/posterior patterning |
| GO:0001657 | ureteric bud development |