| Tag | Content |
|---|---|
| Uniprot ID | J9NYK9 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSCAFP00000038378 |
| Ensembl nucleotide ID | ENSCAFG00000000065 |
| Gene name | Growth differentiation factor 11 |
| Gene symbol | GDF11 |
| Organism | Canis lupus familiaris |
| NCBI taxa ID | 9615 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | SRPTCQCRPG LLTPSQIPFA DAVPPSLLSA DPAVQTDGSP LCCHFHFSPK VMFTKVLKAQ 60 LWVYLRPVPR PATVYLQILR LKPLTGEGTA GGGGGGRRHI RIRSLKIELH SRSGHWQSID 120 FKQVLHSWFR QPQSNWGIEI NAFDPSGTDL AVTSLGPGAE GLHPFMELRV LENTKRSRRN 180 LGLDCDEHSS ESRCCRYPLT VDFEAFGWDW IIAPKRYKAN YCSGQCEYMF MQKYPHTHLV 240 QQANPRGSAG PCCTPTKMSP INMLYFNDKQ QIIYGKIPGM VVDRCGCS 288 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | GDF11 | J9NYK9 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | GDF11 | 102178704 | A0A452DM24 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | GDF11 | 10220 | O95390 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Gdf11 | 14561 | Q9Z1W4 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | GDF11 | 451970 | H2Q663 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | GDF11 | F1SPJ6 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Gdf11 | 29454 | Q9Z217 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | gdf11 | 406247 | Q8JFP9 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005615 | extracellular space |
| GO:0005654 | nucleoplasm |
| GO:0032991 | protein-containing complex |
| GO:0005125 | cytokine activity |
| GO:0008083 | growth factor activity |
| GO:0048593 | camera-type eye morphogenesis |
| GO:0048469 | cell maturation |
| GO:0001656 | metanephros development |
| GO:0045596 | negative regulation of cell differentiation |
| GO:0008285 | negative regulation of cell population proliferation |
| GO:0031016 | pancreas development |
| GO:0010862 | positive regulation of pathway-restricted SMAD protein phosphorylation |
| GO:0060021 | roof of mouth development |
| GO:0001501 | skeletal system development |
| GO:0060395 | SMAD protein signal transduction |
| GO:0021512 | spinal cord anterior/posterior patterning |
| GO:0001657 | ureteric bud development |