Gene: KRT5

Basic information

Tag Content
Uniprot ID A0A452DMF8
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSCHIP00000000926
Ensembl nucleotide ID ENSCHIG00000001082
Gene name IF rod domain-containing protein
Gene symbol KRT5
Organism Capra hircus
NCBI taxa ID 9925
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MSRQSTVSFR SGGSRSFSTA SAITPSVSRT SFTSVSRSGG GGGGGFGRVS LGGAYGAGGF 60
GSRSLYNLGG SKRISISASG GGFRNRFGAG AGGGYGFGGG AGSGFGFGGG AGGGGFGLGG 120
GAGFGGGFGG PGFPVCPPGG IQEVTVNQSL LTPLNLQIDP TIQRVRTEER EQIKTLNNKF 180
ASFIDKVRFL EQQNKVLDTK WTLLQEQGTK TVRQNLEPLF EQYINNLRRQ LDGILGERGR 240
LDSELRNMQD LVEDFKNKYE DEINKRTTAE NEFVMLKKDV DAAYMNKVEL EAKINFMKMF 300
FDAELSQMQT HVSDTSVVLS MDNNRSLDLD SIIAEVKAQY EDIANRSRTE AESWYQTKYE 360
ELQQTAGRHG DDLRNTKHEI SEMNRMIQRL RSEIDNVKKQ CANLQNAIAD AEQRGELALK 420
DARNKLAELE DALQKAKQDM ARLLREYQEL MNTKLALDVE IATYRKLLEG EECRWVTRLT 480
SQIHSGLTFD KVWGGGLGGG GSSSFYSSSS GGVGLGSGLG VGGSGFSASS GRSLGFGSGG 540
GSSSSVKFVS TTSSSRKSFK S 561

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologKRT5A5D7M6Bos taurusPredictionMore>>
1:1 orthologKRT5A0A452DMF8Capra hircusPredictionMore>>
1:1 orthologKRT53852P13647Homo sapiensPredictionMore>>
1:1 orthologKrt5110308Q922U2CPOMus musculusPublicationMore>>
1:1 orthologKRT5100352658G1TDN6Oryctolagus cuniculusPredictionMore>>
1:1 orthologKrt5F7FFV2Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005737 cytoplasm
GO:0045095 keratin filament
GO:0005886 plasma membrane
GO:0097110 scaffold protein binding

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0175 Coiled coil
KW-0403 Intermediate filament
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR018039 IF_conserved
IPR039008 IF_rod_dom
IPR042180 IF_rod_dom_coil1B
IPR032444 Keratin_2_head
IPR003054 Keratin_II

PROSITE

PROSITE ID PROSITE Term
PS00226 IF_ROD_1
PS51842 IF_ROD_2

Pfam

Pfam ID Pfam Term
PF00038 Filament
PF16208 Keratin_2_head