Gene: KRT5

Basic information

Tag Content
Uniprot ID G1TDN6
Entrez ID 100352658
Genbank protein ID
Genbank nucleotide ID XM_002711002.3
Ensembl protein ID ENSOCUP00000014968
Ensembl nucleotide ID ENSOCUG00000017421
Gene name Keratin 5
Gene symbol KRT5
Organism Oryctolagus cuniculus
NCBI taxa ID 9986
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MSRQSSVSFR SGGSRSFSAA SAITPSVSRT SFSSVSRSRG GGGSRVSLGG AYGGGGFGSR 60
SLYNLGGSRK ISISTSGGGF RNQFGVGAGG GYGFGGGAGS GFGFGAGMGG GLGLGGGAGF 120
GGGYGGAGFP VCPPGGIQEV TVNQSLLTPL NLQIDPTIQR VRTEEREQIK TLNNKFASFI 180
DKVRFLEQQN KVLDTKWTLL QEQGTKTVRQ SLEPLFEQYI NNLRRQLDSI LGERGRLDSE 240
LRNMQDLVED FKNKYEDEIN KRTTAENEFV MLKKDVDAAY MSKVELEAKV DALMDEINFL 300
KMFYDAELSQ MQTHVSDTSV VLSMDNNRSL DLDSIIAEVK AQYEEIANRS RTEAESWYQT 360
KYEELQQTAG RHGDDLRNTK HEISEMNRMI QRLRSEIDNV KKQCANLQNA IADAEQRGEL 420
ALKDARNKLA ELEEALQKAK QDMARLLREY QELMNVKLAL DVEIATYRKL LEGEECRLSG 480
EGVGPVNISV VTNSISTGYG GGSSFGGGSG FGGGLGGGLG SGLGGGGGGS LYSSSSGGGL 540
GGGLSVGGSG FSASSGRGMG MGFGSSGGSS SSVKFVSTTS SSRRSFKS 588

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologKRT5A5D7M6Bos taurusPredictionMore>>
1:1 orthologKRT5A0A452DMF8Capra hircusPredictionMore>>
1:1 orthologKRT53852P13647Homo sapiensPredictionMore>>
1:1 orthologKrt5110308Q922U2CPOMus musculusPublicationMore>>
1:1 orthologKRT5100352658G1TDN6Oryctolagus cuniculusPredictionMore>>
1:1 orthologKrt5F7FFV2Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005737 cytoplasm
GO:0045095 keratin filament
GO:0005886 plasma membrane
GO:0097110 scaffold protein binding

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0175 Coiled coil
KW-0403 Intermediate filament
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR018039 IF_conserved
IPR039008 IF_rod_dom
IPR042180 IF_rod_dom_coil1B
IPR032444 Keratin_2_head
IPR003054 Keratin_II

PROSITE

PROSITE ID PROSITE Term
PS00226 IF_ROD_1
PS51842 IF_ROD_2

Pfam

Pfam ID Pfam Term
PF00038 Filament
PF16208 Keratin_2_head