| Tag | Content |
|---|---|
| Uniprot ID | Q922U2; Q920F2; |
| Entrez ID | 110308 |
| Genbank protein ID | AAH06780.1; AAL16774.1; |
| Genbank nucleotide ID | NM_027011.2 |
| Ensembl protein ID | ENSMUSP00000023709 |
| Ensembl nucleotide ID | ENSMUSG00000061527 |
| Gene name | Keratin, type II cytoskeletal 5 |
| Gene symbol | Krt5 |
| Organism | Mus musculus |
| NCBI taxa ID | 10090 |
| Cleft type | CPO |
| Developmental stage | |
| Data sources | Manually collected |
| Reference | 11408584; 24867950; |
| Functional description | |
| Sequence | MSRQSSVSFR SGGSRSFSAA SAITPSVSRT SFSSVSRSGG GGGGRISLGG ACGAGGYGSR 60 SLYNVGGSKR ISYSSGGGSF RNQFGAGGFG FGGGAGSGFG FGGGAGSGFG FGGGAGFGGG 120 YGGAGFPVCP PGGIQEVTVN QNLLTPLNLQ IDPTIQRVRT EEREQIKTLN NKFASFIDKV 180 RFLEQQNKVL DTKWALLQEQ GTKTIKQNLD PLFEQYINNL RRQLDGVLGE RGRLDSELRN 240 MQDLVEDYKN KYEDEINKRT TAENEFVMLK KDVDAAYMNK VELEARVDAL MDEINFMKMF 300 FDAELSQMQT HVSDTSVVLS MDNNRSLDLD SIIAEVKAQY EDIANRSRTE AESWYQTKYE 360 ELQQTAGRHG DDLRNTKHEI SEMNRMIQRL RSEIDNVKKQ CANLQNAIAE AEQRGELALK 420 DARNKLTELE EALQKAKQDM ARLLREYQEL MNTKLALDVE IATYRKLLEG EECRLSGEGV 480 GPVNISVVTN SVSSGYGGGS SIGVGSGFGG GLGSGFAGGL GPRFTRGGGG LGLGSGLSVG 540 GSGFSAGSSQ GGMSFGSGGG SGSSVKFVST TSSSRRSFKS |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | KRT5 | A5D7M6 | Bos taurus | Prediction | More>> | |||
| 1:1 ortholog | KRT5 | A0A452DMF8 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | KRT5 | 3852 | P13647 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Krt5 | 110308 | Q922U2 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | KRT5 | 100352658 | G1TDN6 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Krt5 | F7FFV2 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term | Evidence |
|---|---|---|
| GO:0005515 | protein binding | IPI |
| GO:0097110 | scaffold protein binding | ISO |
| GO ID | GO Term | Evidence |
|---|
| GO ID | GO Term | Evidence |
|---|---|---|
| GO:0005737 | cytoplasm | ISO |
| GO:0005739 | mitochondrion | HDA |
| GO:0005882 | intermediate filament | ISO |
| GO:0005886 | plasma membrane | IDA |
| GO:0045095 | keratin filament | ISO |
| GO:0045095 | keratin filament | IDA |
| Reactome ID | Reactome Term | Evidence |
|---|---|---|
| R-MMU-1266738 | Developmental Biology | IEA |
| R-MMU-1500931 | Cell-Cell communication | IEA |
| R-MMU-446107 | Type I hemidesmosome assembly | IEA |
| R-MMU-446728 | Cell junction organization | IEA |
| R-MMU-6805567 | Keratinization | IEA |
| R-MMU-6809371 | Formation of the cornified envelope | IEA |