Gene: KRT5

Basic information

Tag Content
Uniprot ID A5D7M6
Entrez ID
Genbank protein ID AAI40617.1
Genbank nucleotide ID
Ensembl protein ID ENSBTAP00000021456
Ensembl nucleotide ID ENSBTAG00000038384
Gene name KRT5 protein
Gene symbol KRT5
Organism Bos taurus
NCBI taxa ID 9913
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MSRQSTVSFR SGGGRSFSTA SAITPSVSRT SFTSVSRSGG GGGGGFGRVS LGGAYGAGGF 60
GSRSLYNLGG SKRISISASG GGFRNRFGAG AGGGYGFGGG AGSGFGFGGG AGGGGFGLGG 120
GAGFGGGFGG PGFPVCPPGG IQEVTVNQSL LTPLNLQIDP TIQRVRTEER EQIKTLNNKF 180
ASFIDKVRFL EQQNKVLDTK WALLQEQGTK TVRQNLEPLL EQYINNLRRQ LDGIVGERGR 240
LDSELRNMQD LVEDFKNKYE DEINKRTTAE NEFVMLKKDV DAAYMNKVEL EAKVDALMDE 300
INFMKMFFDA ELSQMQTHVS DTSVVLSMDN NRSLDLDSII AEVKAQYEDI ANRSRTEAES 360
WYQTKYEELQ QTAGRHGDDL RNTKHEISEM NRMIQRLRSE IDNVKKQCAN LQNAIADAEQ 420
RGELALKDAR SKLAELEDAL QKAKQDMARL LREYQELMNT KLALDVEIAT YRKLLEGEEC 480
RLSGEGVGPV NISVVTNTVS SGYGGGSGFG SGLGGGLGGG LGGGLGGGLG SGLGGGGSSS 540
FYSSSSGGVG LGGGLSVGGS GFSASSGRSL GFGSGGGSSS SVKFVSTTSS SRKSFKS 597

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologKRT5A5D7M6Bos taurusPredictionMore>>
1:1 orthologKRT5A0A452DMF8Capra hircusPredictionMore>>
1:1 orthologKRT53852P13647Homo sapiensPredictionMore>>
1:1 orthologKrt5110308Q922U2CPOMus musculusPublicationMore>>
1:1 orthologKRT5100352658G1TDN6Oryctolagus cuniculusPredictionMore>>
1:1 orthologKrt5F7FFV2Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005737 cytoplasm
GO:0045095 keratin filament
GO:0005886 plasma membrane
GO:0097110 scaffold protein binding

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0175 Coiled coil
KW-0403 Intermediate filament
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR018039 IF_conserved
IPR039008 IF_rod_dom
IPR042180 IF_rod_dom_coil1B
IPR032444 Keratin_2_head
IPR003054 Keratin_II

PROSITE

PROSITE ID PROSITE Term
PS00226 IF_ROD_1
PS51842 IF_ROD_2

Pfam

Pfam ID Pfam Term
PF00038 Filament
PF16208 Keratin_2_head