| Tag | Content |
|---|---|
| Uniprot ID | A0A452DPA3 |
| Entrez ID | 102174722 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_005679722.3 |
| Ensembl protein ID | ENSCHIP00000001570 |
| Ensembl nucleotide ID | ENSCHIG00000002616 |
| Gene name | Uncharacterized protein |
| Gene symbol | TPH2 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MQPAMMMFSS KYWARRGLSL DSAVPEEHQL LASLTLNKTN SGKNEDKNGN KGSSKNDTAT 60 ESGKTAVVFS LKNEVGGLVK ALKLFQEKHV NMIHIESRKS RRRSSEVEIF VDCECGKTEF 120 NELIQSLKFQ TTIVTLNPPE NIWTEEEELE DVPWFPRKIS ELDRCSHRVL MYGSELDADH 180 PGFKDNVYRQ RRKYFVDVAM GYKYGQPIPR VEYTEEETKT WGVVFRELSK LYPTHACREY 240 LKNFPLLTKH CGYREDNVPQ LEDVAAFLKE RSGFTVRPVA GYLSPRDFLA GLAYRVFHCT 300 QYVRHGSDPL YTPEPDTCHE LLGHVPLLAD PKFAQFSQEI GLASLGASDE DVQKLATCYF 360 FTIEFGLCKQ EGQLRAYGAG LLSSIGELKH ALSDKACVKA FDPKTTCLQE CLITTFQEAY 420 FVSESFEEAK EKMRDFAKSI TRPFSVYFNP YTQSIEILKD TRSIENVVQD LRSDLNTVCD 480 ALNKMNQYLG I 491 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | TPH2 | F1PGH2 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | TPH2 | 102174722 | A0A452DPA3 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | TPH2 | 100009684 | Q0EAB8 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | TPH2 | 121278 | Q8IWU9 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Tph2 | 216343 | Q8CGV2 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | TPH2 | 467070 | A0A2I3TG35 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | TPH2 | F1SH22 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Tph2 | 317675 | Q8CGU9 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | tph2 | 407712 | Q1LUE3 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0043005 | neuron projection |
| GO:0005506 | iron ion binding |
| GO:0004510 | tryptophan 5-monooxygenase activity |
| GO:0009072 | aromatic amino acid family metabolic process |
| GO:0042427 | serotonin biosynthetic process |
| Pfam ID | Pfam Term |
|---|---|
| PF00351 | Biopterin_H |