Gene: LHX6

Basic information

Tag Content
Uniprot ID A0A452EBF4
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSCHIP00000009304
Ensembl nucleotide ID ENSCHIG00000012218
Gene name Uncharacterized protein
Gene symbol LHX6
Organism Capra hircus
NCBI taxa ID 9925
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MAQPGSGCKA TTRCLEGTAP PAMAQSDAEA LAGALDKDEG RASPCTPSTP SVCSPPSAAS 60
SVPSAGKNIC SSCGLEILDR YLLKVNNLIW HVRCLECSVC RTSLRQQNSC YIKNKEIFCK 120
MDYFSRFGTK CARCGRQIYA SDWVRRARGN AYHLACFACF SCKRQLSTGE EFGLVEEKVL 180
CRIHYDTMIE NLKRAAENGN GLTLEGAVPS EQDSQPKPAK RARTSFTAEQ LQVMQAQFAQ 240
DNNPDAQTLQ KLADMTGLSR RVIQVWFQNC RARHKKHTPQ HPVPPSGAPP SRLPSALSDD 300
IHYSPFSSPE RARMVTLHGY IESQVQCGQV HCRLPYTAPP VHLKADMDGP LSNRGEKVNG 360
ARLGGVGQTP PPPPPGSGFW QASRH 385

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologLHX6541261E1B8I6Bos taurusPredictionMore>>
1:1 orthologLHX6E2RA99Canis lupus familiarisPredictionMore>>
1:1 orthologLHX6A0A452EBF4Capra hircusPredictionMore>>
1:1 orthologLHX626468Q9UPM6Homo sapiensPredictionMore>>
1:1 orthologLhx616874Q9R1R0CPOE14.5Mus musculusPublicationMore>>
1:1 orthologLHX6735560A0A2I3RGU2Pan troglodytesPredictionMore>>
1:1 orthologLhx6D3ZDG6Rattus norvegicusPredictionMore>>
1:1 orthologlhx6445565Q6BDC4Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005634 nucleus
GO:0046872 metal ion binding
GO:0043565 sequence-specific DNA binding
GO:0006355 regulation of transcription, DNA-templated

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0238 DNA-binding
KW-0371 Homeobox
KW-0440 LIM domain
KW-0479 Metal-binding
KW-0539 Nucleus
KW-1185 Reference proteome
KW-0677 Repeat
KW-0862 Zinc

Interpro

InterPro ID InterPro Term
IPR009057 Homeobox-like_sf
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR001781 Znf_LIM

PROSITE

PROSITE ID PROSITE Term
PS00027 HOMEOBOX_1
PS50071 HOMEOBOX_2
PS00478 LIM_DOMAIN_1
PS50023 LIM_DOMAIN_2

Pfam

Pfam ID Pfam Term
PF00046 Homeodomain
PF00412 LIM