| Tag | Content |
|---|---|
| Uniprot ID | Q6BDC4 |
| Entrez ID | 445565 |
| Genbank protein ID | AAT90495.1; AAI62225.1; |
| Genbank nucleotide ID | NM_001004015.2 |
| Ensembl protein ID | ENSDARP00000017657; ENSDARP00000148366; |
| Ensembl nucleotide ID | ENSDARG00000112520; ENSDARG00000006896; |
| Gene name | LIM homeobox 6 |
| Gene symbol | lhx6 |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MYWKNEALAP LSEGNQFLSE GIPSKQVISP DSHSTPGASR CVDGQHGQAM SQSDGESHRS 60 NMEKDDTRSS PSPPSTPSIC SPTSTASSVP STGKNVCASC GLEILDRYLL KVNNLIWHVR 120 CLECSVCRTS LRQHSSCYIK NKEIFCKMDY FSRFGTKCAR CGRQIYASDW VRRARGNAYH 180 LACFACFSCK RQLSTGEEFG LVEEKVLCRI HYDTMVENLK RAAESGSGLT LEGAVPSEQD 240 SQPKPAKRAR TSFTAEQLQV MQAQFAQDNN PDAQTLQKLA DMTGLSRRVI QVWFQNCRAR 300 HKKHTPQHNG PPQAHPQARM PPSLPDELHY SPFGSPERAR MVALHGYIDS HPFSVLTTQS 360 LPHQAMTLPQ LPLSR 375 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | LHX6 | 541261 | E1B8I6 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | LHX6 | E2RA99 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | LHX6 | A0A452EBF4 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | LHX6 | 26468 | Q9UPM6 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Lhx6 | 16874 | Q9R1R0 | CPO | E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | LHX6 | 735560 | A0A2I3RGU2 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | Lhx6 | D3ZDG6 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | lhx6 | 445565 | Q6BDC4 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO:0046872 | metal ion binding |
| GO:0000977 | RNA polymerase II transcription regulatory region sequence-specific DNA binding |
| GO:0021884 | forebrain neuron development |
| GO:0030182 | neuron differentiation |
| GO:0006357 | regulation of transcription by RNA polymerase II |