| Tag | Content |
|---|---|
| Uniprot ID | D3ZDG6 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSRNOP00000008817 |
| Ensembl nucleotide ID | ENSRNOG00000005996 |
| Gene name | LIM homeobox 6 |
| Gene symbol | Lhx6 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MYWKHESAAP ALPEGCRLPA EGGPTTDQVM AQPGSGCKAT TRCLEGTAPP AMAQSDAEAL 60 AGALDKDEGR ASPCTPSTPS VCSPPSAASS VPSAGKNICS SCGLEILDRY LLKVNNLIWH 120 VRCLECSVCR TSLRQQNSCY IKNKEIYCKM DYFSRFGTKC ARCGRQIYAS DWVRRARGNA 180 YHLACFACFS CKRQLSTGEE FGLVEEKVLC RIHYDTMIEN LKRAAENGNG LTLEGAVPSE 240 QDSQPKPAKR ARTSFTAEQL QVMQAQFAQD NNPDAQTLQK LADMTGLSRR VIQVWFQNCR 300 ARHKKHTPQH PVPPSGAPPS RLPSSLSDDI HYSPFSSPER ARMVTLHGYI ESQVQCGQVH 360 CRLPYTAPPV HLKADMDGPL SSRGEKVILF QY 392 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | LHX6 | 541261 | E1B8I6 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | LHX6 | E2RA99 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | LHX6 | A0A452EBF4 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | LHX6 | 26468 | Q9UPM6 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Lhx6 | 16874 | Q9R1R0 | CPO | E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | LHX6 | 735560 | A0A2I3RGU2 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | Lhx6 | D3ZDG6 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | lhx6 | 445565 | Q6BDC4 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO:0046872 | metal ion binding |
| GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding |
| GO:0048469 | cell maturation |
| GO:0021853 | cerebral cortex GABAergic interneuron migration |
| GO:0021895 | cerebral cortex neuron differentiation |
| GO:0021799 | cerebral cortex radially oriented cell migration |
| GO:0021800 | cerebral cortex tangential migration |
| GO:0021884 | forebrain neuron development |
| GO:0021877 | forebrain neuron fate commitment |
| GO:0030182 | neuron differentiation |
| GO:0045944 | positive regulation of transcription by RNA polymerase II |