| Tag | Content |
|---|---|
| Uniprot ID | E2RA99 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSCAFP00000030074 |
| Ensembl nucleotide ID | ENSCAFG00000020277 |
| Gene name | LIM homeobox 6 |
| Gene symbol | LHX6 |
| Organism | Canis lupus familiaris |
| NCBI taxa ID | 9615 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MAQPGSGCKA TTRCLEGTAP PAMAQSDAEA LAGALDKDEG RASPCTPSTP SVCSPPSAAS 60 SVPSAGKNIC ASCGLEILDR DLLKVNNLIW HVRCLECSVC RTSLRQQNSC YIKNKEIFCK 120 MDYFSRFGTK CARCGRQIYA SDWVRRARGN AYHLACFACF SCKRQLSTGE EFGLVEEKVL 180 CRIHYDTMIE NLKRAAENGN GLTLEGAVPS EQDSQPKPAK RARTSFTAEQ LQVMQAQFAQ 240 DNNPDAQTLQ KLADMTGLSR RVIQVWFQNC RARHKKHTPQ HPVPPSGAPP SRLPSALPED 300 IHYSPFSSPE RARMVTLHGY IESQVQCGQV HCRLPYTAPP VHLKADMDGP LSNRGEKVIL 360 FQY 363 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | LHX6 | 541261 | E1B8I6 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | LHX6 | E2RA99 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | LHX6 | A0A452EBF4 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | LHX6 | 26468 | Q9UPM6 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Lhx6 | 16874 | Q9R1R0 | CPO | E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | LHX6 | 735560 | A0A2I3RGU2 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | Lhx6 | D3ZDG6 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | lhx6 | 445565 | Q6BDC4 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO:0046872 | metal ion binding |
| GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding |
| GO:0021884 | forebrain neuron development |
| GO:0030182 | neuron differentiation |
| GO:0045944 | positive regulation of transcription by RNA polymerase II |