| Tag | Content |
|---|---|
| Uniprot ID | A0A452EC64 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSCHIP00000009608 |
| Ensembl nucleotide ID | ENSCHIG00000012408 |
| Gene name | Uncharacterized protein |
| Gene symbol | FZD1 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | LHSKPTLCAR AVPRPLLPLP PPPSPQYNGE RGISIPDHGY CQPISIPLCT DIAYNQTIMP 60 NLLGHTNQED AGLEVHQFYP LVKVQCSAEL KFFLCSMYAP VCTVLEQALP PCRSLCERAR 120 QGCEALMNKF GFQWPDTLKC EKFPVHGAGE LCVGQNTSDK GTPTPSLLPE FWTRHRGGGF 180 AGGAGAADRG KFSCPRALKV PSYLNYHFLG EKDCGAPCEP TKVYGLMYFG PEELRFSRTW 240 IGIWSVLCCA STLFTVLTYL VDMRRFSYPE RPIIFLSGCY TAVAVAYIAG FLLEDRVVCN 300 DKFAEDGART VAQGTKKEGC TILFMMLYFF SMASSIWWVI LSLTWFLAAG MKWGHEAIEA 360 NSQYFHLAAW AVPAIKTITI LALGQVDGDV LSGVCFVGLN NVDALRGFVL APLFVYLFIG 420 TSFLLAGFVS LFRIRTIMKH DGTKTEKLEK LMVRIGVFSV LYTVPATIVI ACYFYEQAFR 480 DQWERSWVAQ SCKSYAIPCP HLPDFTVFMI KYLMTLIVGI TSGFWIWSGK TLNSWRKFYT 540 RLTNSKQGET TV 552 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | FZD1 | 445417 | A7MB15 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | FZD1 | 482294 | F1PCN5 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | FZD1 | A0A452EC64 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | FZD1 | 8321 | Q9UP38 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Fzd1 | 14362 | O70421 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | Fzd1 | 58868 | G3V833 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0009986 | cell surface |
| GO:0016021 | integral component of membrane |
| GO:0005109 | frizzled binding |
| GO:0030165 | PDZ domain binding |
| GO:0042813 | Wnt-activated receptor activity |
| GO:0017147 | Wnt-protein binding |
| GO:0035425 | autocrine signaling |
| GO:0044338 | canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation |
| GO:0044339 | canonical Wnt signaling pathway involved in osteoblast differentiation |
| GO:0007275 | multicellular organism development |
| GO:0051091 | positive regulation of DNA-binding transcription factor activity |
| GO:0045893 | positive regulation of transcription, DNA-templated |
| GO:0042493 | response to drug |