Gene: TNS1

Basic information

Tag Content
Uniprot ID A0A452EMY6
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSCHIP00000013172
Ensembl nucleotide ID ENSCHIG00000014628
Gene name Uncharacterized protein
Gene symbol TNS1
Organism Capra hircus
NCBI taxa ID 9925
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MSTSRTTEDS CELDLVYVTE RIIAVSFPST ANEENFRSNL REVAQMLKSK HGGNYLLFNL 60
SERRPDITKL HAKVLEFGWP DLHTPALEKI CSVCKAMDTW LNADPHNVVV LHNKGNRGRI 120
GVVIAAYMHY SNISASADQA LDRFAMKRFY EDKIVPIGQP SQRRYVHYFS GLLSGSIKMN 180
NKPLFLHHVI MHGIPNFESK GGCRPFLRIY QAMQPVYTSG IYNVQGDSQT SICITIEPGL 240
LLKGDILLKC YHKKFRSPAR DVIFRVQFHT CAIHDLGVVF GKEDLDDAFK DDRFPEYGKV 300
EFVFSYGPEK IQGMEHLENG PSVSVDYNTS DPLIRWDSYD NFNGHRDDGM EEVVGHTQGP 360
LDGSLYAKVK KKDSLHGSTG AVNATRPVLS ATPNHVEHTL SVSSDSGNST ASTKTDKTDE 420
PAPGPASAPA ALSPEEKREL DRLLSGFGLE REKQGAMYHP QHLRSRPVGG PAAPSSGRHI 480
VPAQVHVNGG ALASERETDI LDDELPNQDG HSVGSMGTLS SLDGVTNTSE GGYPEALSPL 540
TNGLDKPYPT EPMVNGGGYP YESASRAVPA QAGHTAPMRP SYSAQEGLAG YQREGPHPAW 600
PQSATTSHYG HDANGMFRSQ SFPETEPQLP PAPARGGSSR EAHQQQQQQQ QQQQQQPRPP 660
PRQQERAHLE SLGLSRPSPQ PLAEPSMSGL PEFPRAASQQ EIEQSIEALN MLMLDLEPAT 720
AGAPLHKSQS VPGAWPGASP LSSQPFSGSS CQSHPLTQSR SGYIPSGHSL GTPEPAPRAS 780
LESVPTGRPY SPYDYQPCPT GPNQSYHPKS LATSSSPAFL PTTQSSLGPQ QPPASLPGLT 840
TQPQLPPKEV TSDPSRTPEE QPLNLEGLVA HRVAGVQARE KQPAEPPAPL RKRAASDGQY 900
ENQSPEPTSP RSPGVRSPVQ CVSPELALTI ALNPGGRPKE PHLHSYKEAF EEMEGTSPTS 960
PPPSGVRSPP GLAKTPLSAL GLKPHNPADI LLHPTGRRLG RPEDRVGNWR TPVVLEPRSY 1020
VESVVRTAVA GPRTQEPEPK SFSTPAVQAY GNETPLRNGT LGGSFVSPSP LSTSSPILSA 1080
DSTSVGSFPS GESSDQGART PTQPLLDSGF RSSSLGQPSP LAQRNYQSSS PLPAAGSSYS 1140
SPDYSLQQFS SPEGQARAQF SVAGVHTVPG SPQARHRTVG TNTPPSPGFG RRAVNPSLAA 1200
PSSPSMSHRQ VTGPLGTGFH VNAGSSPQGS AATTPGSPSL GRHPGAHQVS NLHGNVVTAP 1260
GSPSLGRHPG AHPGTLPSNL HGNAVASPGS PSLGRHLGGS GSVVPGSPSL DRHVPYGGYS 1320
TPEDRRPTLS RQSSASGYQA PSTPSFPVSP AYYPGLSSPT TSPSPDSAAF RQGSPTPALP 1380
EKRRMSMGDR AGSLPNYATV NGKVSSSPVA SGMSSPSGGS TVSFSHTLPD FSKYSMPDNS 1440
PETRAKVKFV QDTSKYWYKP EISREQAIAL LKDQEPGAFI IRDSHSFRGA YGLAMKVSSP 1500
PPTIMQQNKK GDMTHELVRH FLIETGPRGV KLKGCPNEPN FGSLSALVYQ HSIIPLALPC 1560
KLVIPNRDPT DESKDSSGPA NSTSDLLKQG AACNVLFVNS VDMESLTGPQ AISKATSETL 1620
AADPTPAATI VHFKVSAQGI TLTDNQRKLF FRRHYPLNTV TFCDLDPQER KWTKTEGGAP 1680
AKLFGFVARK QGSATDNACH LFAELDPSQP ASAIVSFVSK VMLSASQRR 1729

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologTNS1A0A452EMY6Capra hircusPredictionMore>>
1:1 orthologTNS17145Q9HBL0Homo sapiensPublicationMore>>
1:1 orthologTns1A0A087WQ94Mus musculusPredictionMore>>
1:1 orthologTNS1459934A0A2I3SUI0Pan troglodytesPredictionMore>>
1:1 orthologTns1301509F1LN42Rattus norvegicusPredictionMore>>
1:1 orthologtns1bF1Q649Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1185 Reference proteome
KW-0727 SH2 domain

Interpro

InterPro ID InterPro Term
IPR011993 PH-like_dom_sf
IPR029021 Prot-tyrosine_phosphatase-like
IPR013625 PTB
IPR006020 PTB/PI_dom
IPR000980 SH2
IPR036860 SH2_dom_sf
IPR035012 Tensin-like_SH2
IPR014020 Tensin_C2-dom
IPR029023 Tensin_phosphatase
IPR033929 Tensin_PTB
IPR003595 Tyr_Pase_cat

PROSITE

PROSITE ID PROSITE Term
PS51182 C2_TENSIN
PS51181 PPASE_TENSIN
PS50001 SH2

Pfam

Pfam ID Pfam Term
PF08416 PTB
PF10409 PTEN_C2
PF00017 SH2