| Tag | Content |
|---|---|
| Uniprot ID | F1LN42 |
| Entrez ID | 301509 |
| Genbank protein ID | |
| Genbank nucleotide ID | NM_001191810.1 |
| Ensembl protein ID | ENSRNOP00000032812 |
| Ensembl nucleotide ID | ENSRNOG00000014182 |
| Gene name | Tensin 1 |
| Gene symbol | Tns1 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MGCTVSLVCC EALEPLPSCG PQPPGTPPGP ARPERSEPGG AASIQRRRLL LQPEDLEAPK 60 THHFKVKAFK KVKPCGVCRQ AITREGCICK VCSFSCHRKC QAKVAAPCVP PSSHELVPIA 120 TESVPKNVVD VGEGDCRGGS TPKNLEEAGS MRVSPSIQPQ PQPQPQPISL SRNLSVSRAM 180 EDSCELDLVY ITERIIAVSF PSTANEENFR SNLREVAQML KSKHGGNYLL FNLSEQRPDI 240 TKLHAKVLEF GWPDLHTPAL EKICSVCKAM DTWLNADPHN VVVLHNKGNR GRIGVVIAAY 300 MHYSNISASA DQALDRFAMK RFYEDKIVPI GQPSQRRYVH YFSGLLSGSI KMNNKPLFLH 360 HVIMHGIPNF ESKGGCRPFL RIYQAMQPVY TSGIYNIPGD SQASICITIE PGLLLKGDIL 420 LKCYHKKFRS PARDVIFRVQ FHTCAIHDLG VVFGKEDLDE AFKDDRFPDY GKVEFVFSYG 480 PEKIQGMEHL ENGPSVSVDY NTSDPLIRWD SYDNFNGHRE DGMEEVVGHT QGPLDGSLYA 540 KVKKKDSLNG SSGPITTARP ALSATPNHVE HTLSVSSDSG NSTASTKTDK TDEPVSGAAI 600 APAALSPQEK KELDRLLSGF GVDREKQGAM YRAQQLRSHP GGGPTVSSPG RHIVPAQVHV 660 NGGALASERE TDILDDELPI QDGQSGGSMG TLSSLDGVTN TSEGGYPETL SPLTNGLDKP 720 YPTEPILNGG GYPYESANRV VPVHSSHSAP IRPSYSAQEG LGGYQREGPH PAWSKQVTSA 780 HRGYDPSGLF RSQSFPDVEP QLPQAPARGG SSREAVQRGL NSWQQQQQQQ QQQQQQQQQQ 840 QQQQPHPPPR QQERSPLQSL ACSKPSPHLS AETPIPALPE FPRAASQQEI EQSIETLNML 900 MLDLEPASAA APLHKSQSVP GAWPGASPLS SQPLLGSSCQ SHPLTQSRSG YIPSGDTLGA 960 PELLSSGRSY SPYDYQLHPA ASNQSFRPKS PASSTFLPSP HSSAGPQEPP ASLPGLIAEP 1020 QLPLKETTSD TSRTPEEEPL NLEGLVAHRV AGVQARERQP AEPPAPLRRR AASDGQYENQ 1080 SPEATSPRSP GVRSPVQCVS PELALTIALN PGGRPKEPHL HSYKEAFEEM EGTSPSSPPP 1140 SVARSPPGLA KTPLSALGLK PHNPADILLH PTGVARRLIQ PEEDEGEEVA KPPEEPRSYV 1200 ESVARTAVAG PRAQDVEPKS FSAPATHAYG HETPLRNGTP GGSFVSPSPL STSSPILSAD 1260 STSVGSFPSA GSSDQGPRTP IQPMLDSSIR SGSLGQPSPA ALSYQSSSPV PVGGSSYSSP 1320 DYSLQPFSSS PESQGQPHFS AASVHMVPGS PQARHRTVGT NTPPSPGFGR RAINPTMAAP 1380 GSPSLSHRQV MGPSGPGFHG NVVSGHPTSA TVAPGSPSLG RHPVGSHQVP GLHSGVVTTP 1440 GSPSLGRHPG AHQGNLVSSL HGNAVISPGS PSLGRHLGGS GSVVPGSPSL DRHVAYGGYS 1500 TPEDRRPTLS RQSSASGYQA PSTPSFPVSP AYYPGLSSPA TSPSPDSAAF RQGSPTPALP 1560 EKRRMSVGDR AGSLPNYATI NGKVSSSPVA NGMASPSGSS TVSFSHTLPD FSKYSMPDNS 1620 PETRAKVKFV QDTSKYWYKP EISREQAIAL LKDQEPGAFI IRDSHSFRGA YGLAMKVSSP 1680 PPTITQQGKK GDMTHELVRH FLIETGPRGV KLKGCPNEPN FGSLSALVYQ HSVIPLALPC 1740 KLVIPSRDPT DESKDSSGPA NSTTDLLKQG AACNVLFINS VDMESLTGPQ AISKATSETL 1800 AADPTPAATI VHFKVSAQGI TLTDNQRKLF FRRHYPLNTV TFCDLDPQER KWMKTEGGAP 1860 AKLFGFVARK QGSTTDNACH LFAELDPNQP ASAIVNFVSK VMLSAGQKR 1909 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | TNS1 | A0A452EMY6 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | TNS1 | 7145 | Q9HBL0 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Tns1 | A0A087WQ94 | Mus musculus | Prediction | More>> | |||
| 1:1 ortholog | TNS1 | 459934 | A0A2I3SUI0 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | Tns1 | 301509 | F1LN42 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | tns1b | F1Q649 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0030055 | cell-substrate junction |
| GO:0005925 | focal adhesion |
| GO:0046872 | metal ion binding |
| GO:0007044 | cell-substrate junction assembly |
| GO:0010761 | fibroblast migration |
| GO:0035556 | intracellular signal transduction |