Gene: tns1b

Basic information

Tag Content
Uniprot ID F1Q649
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSDARP00000023241
Ensembl nucleotide ID ENSDARG00000020845
Gene name Tensin 1b
Gene symbol tns1b
Organism Danio rerio
NCBI taxa ID 7955
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MATAVFQVSS SCVPVANYEL APSNELPLKH IETTGSTKSS KSMESRRRPS RSLSLIQAME 60
ENYEVDLVYI TERIISVTFP SNAEEPSYSA NIKEVANMLR SKHGDNYLLF NLSEKRLDIS 120
KLNPKVLDFG WPDHHAPALD KICSICKAMD TWMNAGSHNV VVIHNKGNRG RTGVVVAAYM 180
HYSNISASAD QALDRFAMKR FYEDKVLPVG QPSQRRYVQY FSGLLSGHIK INNKPLFLHH 240
VIMHGIPNFE SKGGCRPFLK IYQAMQPVYT SGIYNVQGDS QTSICITIEP GLLLKGDILL 300
KCYHKRFRSP CRDVIFRVQF HTCAVHDLGI VFGKDELDET FKDDRFPEYG KVEFVFSFGP 360
EKIQGMDHLE NGPSVSVDYN TQDALIRWDS YENFNQRCED SMEDVIHTEG PLDGSLYAKV 420
RKKESLEGGV TANGLPAAAD HTLPAVDHTL PPVDHALSVS SDSGNSTASI KTDRTDEASH 480
QPALVSQPSS QPLSPEEKQE LDQLLSGLEA PMHRTGYQSS PGGGGGGGGG VLHLVPAQVH 540
VNGHSNIDRE TDILDDDLPI SQEGNSVDSL GTLSSFEGRA TPADLYYQSE TVINGQDMPY 600
LEKSVHEKML EPRVHSSSSV QEHLGAPSGY ANQNGNIYRS QSLGATPNTD QKYMPKAPAR 660
TTSSRDAVQR LNVWQQFGVP EVPVTDGVTF NPVLQSHSLP EFPQMASQQE IEQSIEALNM 720
LMLDLDPALT QVPKSHSAPS GESGVVTTQP SFSQTQARPS YQADTAIHDR GAASSMGFPL 780
TFQQVTGEPS QPTMKQQKPT TTSQHVEFAS EAGGQAPMSQ STVPSSTFGV LQLKPLNIYP 840
SSTTSQSPEP QETQRSYSSS SSPLPKESEP EDSSYKLEGL VAHRVAGLPS GEMSPDEAAV 900
PGRCRTLSEG LSQDESPTRG SSVRSPIRCI SPELANTIAL NPGGRPKERH MHSYREAFEE 960
MDGGPVSPPP IVGGEVLPQT PAFPVSPQTP YFNMCRSPPG LAKTPLSFLG LKPHNPAEIL 1020
LNQTGSEPRS YVESVAKAAA VPASPTYDSD SLARPAGPSH AYNAPLSSSS PIQNPDPVES 1080
TLADSGVGMN SLSQAAVDIF HFQPSEIPYQ PPPPPYPTSM LGSYISPSPA EAMQNNTTTI 1140
QPLSGSPGTR HHTILSDMAS VPNFQHRLAN QDGPILGRQQ APANGHVPGI AGSPVQGRHT 1200
MVSQGTQSSP ILSRQYPVTQ GIQSSPILSR QPMGQAVQSS PVLNRQASLN QANQSSPVLS 1260
RQQSITLPNQ GSPVLSRQSS LSHPSQGSPV LGRHPSLTQG SPSLDRHPMY SGYTTPEERH 1320
GALSRQSSSS GYQPPSTPSF PVSPAGYIEG AGFRQGSPAF QPQLPEKRRM SSSDRTNGGL 1380
SYGTLNGKMS SPVSSGGSTP SVHFFHTLPD FSKLNMCDGS PETRMNVKFV QDTSKFWYKP 1440
DISRDQAINM LKDQDPGAFV IRDSHSFRGA YGLAMKVASP PPTTQPTKKA GDVTNELVRH 1500
FLIETSPKGV RLKGCPNEPY FGCLSALVYQ HSITPLALPC KLVIPTRDPL EESPEIATPT 1560
NPAADMLKQG AACNVLYINS VDMESLTGPQ AIAKAISETM NASPAPSATI VHFKVSAQGI 1620
TLTDNQRKLF FRRHYPIGTV TFCDIDPQER KWNKPEGGTA KFFGFVARKQ GSTTDNVSHL 1680
FAEMDPDQPA TAIVNFVSKV MISSQKR 1707

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologTNS1A0A452EMY6Capra hircusPredictionMore>>
1:1 orthologTNS17145Q9HBL0Homo sapiensPublicationMore>>
1:1 orthologTns1A0A087WQ94Mus musculusPredictionMore>>
1:1 orthologTNS1459934A0A2I3SUI0Pan troglodytesPredictionMore>>
1:1 orthologTns1301509F1LN42Rattus norvegicusPredictionMore>>
1:1 orthologtns1bF1Q649Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0030054 cell junction

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0965 Cell junction
KW-1267 Proteomics identification
KW-1185 Reference proteome
KW-0727 SH2 domain

Interpro

InterPro ID InterPro Term
IPR011993 PH-like_dom_sf
IPR029021 Prot-tyrosine_phosphatase-like
IPR013625 PTB
IPR006020 PTB/PI_dom
IPR000980 SH2
IPR036860 SH2_dom_sf
IPR035012 Tensin-like_SH2
IPR014020 Tensin_C2-dom
IPR029023 Tensin_phosphatase
IPR033929 Tensin_PTB
IPR003595 Tyr_Pase_cat

PROSITE

PROSITE ID PROSITE Term
PS51182 C2_TENSIN
PS51181 PPASE_TENSIN
PS50001 SH2

Pfam

Pfam ID Pfam Term
PF08416 PTB
PF10409 PTEN_C2
PF00017 SH2