| Tag | Content |
|---|---|
| Uniprot ID | A0A452EQP3 |
| Entrez ID | 100861039 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_018040824.1 |
| Ensembl protein ID | ENSCHIP00000014487 |
| Ensembl nucleotide ID | ENSCHIG00000015476 |
| Gene name | Fe2OG dioxygenase domain-containing protein |
| Gene symbol | PLOD3 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MRACVQLGPL SAMASGPGLR PLLLLLLLLS PSPAASASDR PRGSDPVNPE KLLVITVATA 60 ETEGYRRFLQ SAEFFNYTVR TLGLGEEWRG GDVARTVGGG QKVRWLKKEM EKYAEREDMV 120 IMFVDSYDVV LAGGPSELLK KFVQSGSRLL FSAESFCWPE WGLAEQYPEV GTGKRFLNSG 180 GFIGFAPTIH QIVRQWKYKD DDDDQLFYTR LYLDPGLREK LGLSLDHKSR IFQNLNGALD 240 EVVLKFGRNR VRIRNVAYDT LPVVVHGNGP TKLQLNYLGN YVPNGWTPEG GCGFCNQDRR 300 PLPGGQPPPR VLLAVFVEQP TPFLPRFLQR LLLLDYPPDR VTLFLHNNEV YHEPHIDDSW 360 PQLQDHFSAV KLVGPEEALT PGEARDMAMD ICRQDPKCEF YFSLDADTVI TNPQTLRILI 420 EANRKVIAPM LSRHGKLWSN FWGALSPDEY YARSEDYVEL VQRKRVGVWN VPYISQAYVI 480 RGETLRTELP QREVFSGSDT DPDMAFCKSL RDKGIFLHLS NQHEFGRLLA TSRYDTDHLH 540 PDLWQIFDNP LDWKEQYIHE NYSRALEGEG LVEQPCPDVY WFPLLSEQMC DELVEEMEHF 600 GQWSGGRHED SRLAGGYENV PTVDIHMKQV GYEDQWLQLL RTYVGPMTES LFPGYHTKTR 660 AVMNFVVRYR PDEQPSLRPH HDSSTFTLNV ALNHKGLDYE GGGCRFLRYD CVISSPRKGW 720 GLLHPGRLTH YHEGLPTTRG TRYIMVSFVD P 751 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | PLOD3 | 514996 | F1MET0 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | PLOD3 | 479730 | E2RTL4 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | PLOD3 | 100861039 | A0A452EQP3 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | PLOD3 | 8985 | O60568 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Plod3 | 26433 | Q9R0E1 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | PLOD3 | I3LA84 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Plod3 | 288583 | Q5U367 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | plod3 | 556077 | A3KNH4 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0062023 | collagen-containing extracellular matrix |
| GO:0005783 | endoplasmic reticulum |
| GO:0005615 | extracellular space |
| GO:0005802 | trans-Golgi network |
| GO:0005506 | iron ion binding |
| GO:0031418 | L-ascorbic acid binding |
| GO:0050211 | procollagen galactosyltransferase activity |
| GO:0033823 | procollagen glucosyltransferase activity |
| GO:0008475 | procollagen-lysine 5-dioxygenase activity |
| GO:0070831 | basement membrane assembly |
| GO:0030199 | collagen fibril organization |
| GO:0032963 | collagen metabolic process |
| GO:0001886 | endothelial cell morphogenesis |
| GO:0048730 | epidermis morphogenesis |
| GO:0046947 | hydroxylysine biosynthetic process |
| GO:0001701 | in utero embryonic development |
| GO:0060425 | lung morphogenesis |
| GO:0021915 | neural tube development |
| GO:0017185 | peptidyl-lysine hydroxylation |
| GO:0008104 | protein localization |
| GO:0006493 | protein O-linked glycosylation |
| GO:0042311 | vasodilation |
| Pfam ID | Pfam Term |
|---|---|
| PF03171 | 2OG-FeII_Oxy |