Gene: PLOD3

Basic information

Tag Content
Uniprot ID I3LA84
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSSSCP00000020951
Ensembl nucleotide ID ENSSSCG00000028879
Gene name Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3
Gene symbol PLOD3
Organism Sus scrofa
NCBI taxa ID 9823
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MASGPGLRLL LLPLLVLSPP PAASASDRPR GSDPVNPDKL LVITVATAET EGYRRFLRSA 60
EFFNYTVRTL GLGEEWRGGD VARTVGGGQK VRWLKKEMEK YADREDMVIM FVDSYDVLLA 120
GSPSELLKKF VQSGSRLLFS AEGFCWPEWG LAEQYPEVGT GKRFLNSGGF IGFAPVIHQI 180
VRQWKYKDDD DDQLFYTRLY LDPGLREKLG LNLDHKSRIF QNLNGALDEV VLKFGRNRVR 240
IRNVAYDTLP VVVHGNGPTK LQLNYLGNYV PNGWTPEGGC GFCDLDRRTL PGGQPPPRVL 300
LAVFVEQPTP FLPRFLQRLL LLDYPPDRVT LFLHNNEVYH EPHIAASWPQ LQDHFSAVKL 360
VGPEEALTPG EARDMAMDTC RRDPKCEFYF SLDADAVITN PQVLRILIEE NRKVIAPMLS 420
RHGKLWSNFW GALSPDEYYA RSEDYVELVQ RKRVGVWNVP YISQAYVIRG ETLRTELPQR 480
EVFSGSDTDP DMAFCKSVRD KGIFLHLSNR HEFGRLLATS RYDTDHLHPD LWQIFDNPLD 540
WKEQYIHENY SRALEGEGLV EQPCPDVYWF PLLSEQMCDE LVEEMEHYGQ WSGGRHEDSR 600
LAGGYENVPT VDIHMKQVGY EDQWLQLLRT YVGPMTESLF PGYHTKTRAV MNFVVRYRPD 660
EQPSLRPHHD SSTFTLNVAL NHKGLDYEGG GCRFLRYDCV ISSPRKGWGL LHPGRLTHYH 720
EGLPTTRGTR YIMVSFVDP 739

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologPLOD3514996F1MET0Bos taurusPredictionMore>>
1:1 orthologPLOD3479730E2RTL4Canis lupus familiarisPredictionMore>>
1:1 orthologPLOD3100861039A0A452EQP3Capra hircusPredictionMore>>
1:1 orthologPLOD38985O60568Homo sapiensPredictionMore>>
1:1 orthologPlod326433Q9R0E1CPOMus musculusPublicationMore>>
1:1 orthologPLOD3I3LA84Sus scrofaPredictionMore>>
1:1 orthologPlod3288583Q5U367Rattus norvegicusPredictionMore>>
1:1 orthologplod3556077A3KNH4Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005783 endoplasmic reticulum
GO:0005506 iron ion binding
GO:0031418 L-ascorbic acid binding
GO:0033823 procollagen glucosyltransferase activity
GO:0008475 procollagen-lysine 5-dioxygenase activity
GO:0017185 peptidyl-lysine hydroxylation

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1267 Proteomics identification
KW-1185 Reference proteome
KW-0732 Signal

Interpro

InterPro ID InterPro Term
IPR029044 Nucleotide-diphossugar_trans
IPR005123 Oxoglu/Fe-dep_dioxygenase
IPR006620 Pro_4_hyd_alph
IPR001006 Procol_lys_dOase

PROSITE

PROSITE ID PROSITE Term
PS51471 FE2OG_OXY
PS01325 LYS_HYDROXYLASE

Pfam

Pfam ID Pfam Term
PF03171 2OG-FeII_Oxy