Gene: PLOD3

Basic information

Tag Content
Uniprot ID E2RTL4
Entrez ID 479730
Genbank protein ID
Genbank nucleotide ID XM_536856.5
Ensembl protein ID ENSCAFP00000020467
Ensembl nucleotide ID ENSCAFG00000013860
Gene name Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3
Gene symbol PLOD3
Organism Canis lupus familiaris
NCBI taxa ID 9615
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MASSGPGLRL LLGLLLLLPP PPATSASDRP RGGDPVNPEK LLVITVATAE TEGYRRFLWS 60
AEFFNYTVRT LGLGEEWRGG DVARTVGGGQ KVRWLKKEME KYADREDMVI MFVDSYDVIL 120
AGSPAELLKK FVQSGSRLLF SAEGFCWPEW GLAEQYPEVG TGKRFLNSGG FIGFAPTIHK 180
VVRQWKYKDD DDDQLFYTRL YLDPGLREKL SLNLDHKSRI FQNLNGALDE VVLKFDRNRV 240
RIRNVAYDTL PVVVHGNGPT KLHLNYLGNY VPNGWTPQGG CGFCGRDRRT LPGGQPPPRV 300
LLAVFVEQPT PFLPRFLQRL LLLDYPPDRV TLFLHNNEVY HEPHIADSWP QLQDHFSAVK 360
LVGPEEALTP GEARDMAMDS CRQDPECEFY FSLDADAVIT NPQTLRILIE ENRKVIAPML 420
SRHGKLWSNF WGALSPDEYY ARSEDYVELV QRKRVGVWNV PYISQAYVIR GETLRTELPQ 480
REVFSGSDTD PDMAFCKSLR DKGIFLHLSN QHEFGRLLAT SRYDTDHLHP DLWQIFDNPL 540
DWKEQYIHEN YSRALEGEGL VEQPCPDVYW FPLLSDQMCD ELVEEMEHYG QWSGGRHEDS 600
RLAGGYENVP TVDIHMKQVG YEDQWLQLLR TYVGPMTESL FPGYHTKTRA VMNFVVRYRP 660
DEQPSLRPHH DSSTFTLNVA LNHKGLDYEG GGCRFLRYDC IVSSPRKGWG LLHPGRLTHY 720
HEGLPTTRGT RYIMVSFVDP

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologPLOD3514996F1MET0Bos taurusPredictionMore>>
1:1 orthologPLOD3479730E2RTL4Canis lupus familiarisPredictionMore>>
1:1 orthologPLOD3100861039A0A452EQP3Capra hircusPredictionMore>>
1:1 orthologPLOD38985O60568Homo sapiensPredictionMore>>
1:1 orthologPlod326433Q9R0E1CPOMus musculusPublicationMore>>
1:1 orthologPLOD3I3LA84Sus scrofaPredictionMore>>
1:1 orthologPlod3288583Q5U367Rattus norvegicusPredictionMore>>
1:1 orthologplod3556077A3KNH4Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005783 endoplasmic reticulum
GO:0005506 iron ion binding
GO:0031418 L-ascorbic acid binding
GO:0033823 procollagen glucosyltransferase activity
GO:0008475 procollagen-lysine 5-dioxygenase activity
GO:0017185 peptidyl-lysine hydroxylation

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1185 Reference proteome
KW-0732 Signal

Interpro

InterPro ID InterPro Term
IPR029044 Nucleotide-diphossugar_trans
IPR005123 Oxoglu/Fe-dep_dioxygenase
IPR006620 Pro_4_hyd_alph
IPR001006 Procol_lys_dOase

PROSITE

PROSITE ID PROSITE Term
PS51471 FE2OG_OXY
PS01325 LYS_HYDROXYLASE

Pfam

Pfam ID Pfam Term
PF03171 2OG-FeII_Oxy