| Tag | Content |
|---|---|
| Uniprot ID | A3KNH4 |
| Entrez ID | 556077 |
| Genbank protein ID | AAI33840.1 |
| Genbank nucleotide ID | NM_001044343.2 |
| Ensembl protein ID | ENSDARP00000080199 |
| Ensembl nucleotide ID | ENSDARG00000076317 |
| Gene name | Procollagen-lysine 5-dioxygenase |
| Gene symbol | plod3 |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MTPVPVILTV ILAVIQLSRT EPRKPNELLV ITAATEVTDG YLRFMRTIRQ FNYTIQVLGL 60 GEQWRGGDVA RTVGGGQKVR WLKTELEKHK DKQNTVIMFV DSYDVILASG PVELLRKFSR 120 FSHRVVFSAE GFCWPDQRLA SKYPAVHHGK RYLNSGGFIG FAPEIHAIVQ QWKYKDDDDD 180 QLFYTRIYLD KEKRRKFNMT LDHRSQIFQN LNGAIEEVVL KFEKSRVRVR NVAYDTLPVV 240 IHGNGPTKLQ LNYLGNYVPT AWTYENGCGI CEEDLLDLSH LSDEEMPLVH VAVFIEQPMP 300 FLEEFLERLA TLNYPHTRIR LFLHNNVVYH EQHVERFWTR HRSLFTGARI VGPEENLKHD 360 QARTMAVEAC KKDVSCDYFF SLDADVALTN PDVLRILIEE NKSVIAPMLS RHGKLWSNFW 420 GALSPEGFYS RAEDYIDIVQ SKRVGLWNVP YITQVYLIRG ETLRSRLAAV SLYQQEGMDP 480 DMSFCKSVRE QGIFMFVSNR DEFGRLVSSA NYNISRLHPD MWQIFDNPVD WREKYIHENY 540 SRIFEDDESV VEQPCPDVYW FPAFSERMCD DLVETMEEFG QWSGGGHKDE RLSGGYENVP 600 TVDIHMNQIQ FEKEWLKFLK EYIVPVTEKL YPGYYPKAQA VMNFVVRYRP DEQPSLRPHH 660 DSSTFTINIA LNSKGVDYEG GGCRFLRYNC KVESPRKGWS FMHPGRLTHY HEGLPTTRGT 720 RYIMVSFVDP |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | PLOD3 | 514996 | F1MET0 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | PLOD3 | 479730 | E2RTL4 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | PLOD3 | 100861039 | A0A452EQP3 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | PLOD3 | 8985 | O60568 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Plod3 | 26433 | Q9R0E1 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | PLOD3 | I3LA84 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Plod3 | 288583 | Q5U367 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | plod3 | 556077 | A3KNH4 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005783 | endoplasmic reticulum |
| GO:0005789 | endoplasmic reticulum membrane |
| GO:0005506 | iron ion binding |
| GO:0031418 | L-ascorbic acid binding |
| GO:0033823 | procollagen glucosyltransferase activity |
| GO:0008475 | procollagen-lysine 5-dioxygenase activity |
| GO:0008045 | motor neuron axon guidance |
| GO:0001755 | neural crest cell migration |
| GO:0017185 | peptidyl-lysine hydroxylation |
| Pfam ID | Pfam Term |
|---|---|
| PF03171 | 2OG-FeII_Oxy |