Gene: ASS1

Basic information

Tag Content
Uniprot ID A0A452F1Z3
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSCHIP00000018347
Ensembl nucleotide ID ENSCHIG00000017801
Gene name Uncharacterized protein
Gene symbol ASS1
Organism Capra hircus
NCBI taxa ID 9925
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MSGKGSVVLA YSGGLDTSCI LVWLKEQGYD VIAYLANIGQ KEDFEEARKK ALKLGAKKVF 60
IEDISKEFVE EFIWPAIQSS ALYEDRYLLG TSLARPCIAR KQVEIAQREG AKYVSHGATG 120
KGNDQIRFEL TCYSLAPQIK VIAPWRMPEF YNRFQGRNDL MEYAKQHGIP VPVTPKNPWS 180
MDENLMHIRG LQETDLAQLG WDTLSSNLFL SCQNQAPPGL YTKTQDPAKA PNSPDTLEIE 240
FKKGVPVKVT NVGDGTTHST ALELFLYLNE VAGKHGVGRI DIVENRFIGM KSRGIYETPA 300
GTILYHAHLD IEAFTMDREV RKIKQGLGLK FAELVYTGFW HSPECEFVRH CIAKSQERVE 360
GKVHVSVLKG QVYILGRESP LSLYNEELVS MNVQGDYEPV DATGFININS LRLKEYHRLQ 420
NKVTAK 426

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologASS1280726P14568Bos taurusPredictionMore>>
1:1 orthologASS1A0A452F1Z3Capra hircusPredictionMore>>
1:1 orthologASS1445P00966CL/PHomo sapiensPublicationMore>>
1:1 orthologAss111898P16460E14.5Mus musculusPredictionMore>>
1:1 orthologASS1743223H2QY18Pan troglodytesPredictionMore>>
1:1 ortholog414411A0A480HLI7Sus scrofaPredictionMore>>
1:1 orthologAss125698P09034Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005829 cytosol
GO:0005739 mitochondrion
GO:0016597 amino acid binding
GO:0004055 argininosuccinate synthase activity
GO:0005524 ATP binding
GO:0042802 identical protein binding
GO:0006526 arginine biosynthetic process
GO:0000053 argininosuccinate metabolic process
GO:0006531 aspartate metabolic process
GO:0071499 cellular response to laminar fluid shear stress
GO:0007623 circadian rhythm
GO:0000052 citrulline metabolic process
GO:1903038 negative regulation of leukocyte cell-cell adhesion
GO:0045429 positive regulation of nitric oxide biosynthetic process
GO:0000050 urea cycle

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR001518 Arginosuc_synth
IPR018223 Arginosuc_synth_CS
IPR023434 Arginosuc_synth_type_1_subfam
IPR024074 AS_cat/multimer_dom_body
IPR014729 Rossmann-like_a/b/a_fold

PROSITE

PROSITE ID PROSITE Term
PS00564 ARGININOSUCCIN_SYN_1
PS00565 ARGININOSUCCIN_SYN_2

Pfam

Pfam ID Pfam Term
PF00764 Arginosuc_synth