Gene: WNT3

Basic information

Tag Content
Uniprot ID A0A452F7A0
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSCHIP00000020030
Ensembl nucleotide ID ENSCHIG00000018818
Gene name Protein Wnt
Gene symbol WNT3
Organism Capra hircus
NCBI taxa ID 9925
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description Ligand for members of the frizzled family of seven transmembrane receptors.
Sequence
KCRYPLSACR SLALGQQYTS LGSQPLLCGS IPGLVPKQLR FCRNYIEIMP SVAEGVKLGI 60
QECQHQFRGR RWNCTTIDDS LAIFGPVLDK ATRESAFVHA IASAGVAFAV TRSCAEGTST 120
ICGCDSHHKG PPGEGWKWGG CSEDADFGVL VSREFADARE NRPDARSAMN KHNNEAGRTT 180
ILDHMHLKCK CHGLSGSCEV KTCWWAQPDF RAIGDFLKDK YDSASEMVVE KHRESRGWVE 240
TLRAKYALFK PPTERDLVYY ENSPNFCEPN PETGSFGTRD RTCNVTSHGI DGCDLLCCGR 300
GHNTRTEKRK EKCHCIFHWC CYVSCQECVR IYDVHTCK 338

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologWNT3A0A452F7A0Capra hircusPredictionMore>>
1:1 orthologWNT37473P56703CL/PHomo sapiensPublicationMore>>
1:1 orthologWnt322415P17553Mus musculusPredictionMore>>
1:1 orthologA0A4X1TEB6Sus scrofaPredictionMore>>
1:1 orthologWNT3100009033G1T851Oryctolagus cuniculusPredictionMore>>
1:1 orthologWnt324882D3ZCR1Rattus norvegicusPredictionMore>>
1:1 orthologwnt3569420B0LK22Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005576 extracellular region
GO:0005102 signaling receptor binding
GO:0007275 multicellular organism development
GO:0016055 Wnt signaling pathway

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0217 Developmental protein
KW-1015 Disulfide bond
KW-0272 Extracellular matrix
KW-1185 Reference proteome
KW-0964 Secreted
KW-0879 Wnt signaling pathway

Interpro

InterPro ID InterPro Term
IPR005817 Wnt
IPR009141 Wnt3
IPR043158 Wnt_C
IPR018161 Wnt_CS

PROSITE

PROSITE ID PROSITE Term
PS00246 WNT1

Pfam

Pfam ID Pfam Term
PF00110 wnt