Gene: OSR2

Basic information

Tag Content
Uniprot ID A0A452F9L8
Entrez ID 102177997
Genbank protein ID
Genbank nucleotide ID XM_005689206.2
Ensembl protein ID ENSCHIP00000020986
Ensembl nucleotide ID ENSCHIG00000019458
Gene name Uncharacterized protein
Gene symbol OSR2
Organism Capra hircus
NCBI taxa ID 9925
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MGSKALPAPI PLHPSLQLTN YSFLQAVNTF PAAVDHLQGL YGLSAVQTMH MNHWTLGYPN 60
VHEITRSTIT EMAAAQGLVD ARFSFPALPF TTHLFHPKQG AIAHVLPALH KDRPRFDFAN 120
LAVAATQEDP PKIADLSKLS PGLGSPISGL SKLTPDRKPS RGRLPSKTKK EFICKFCGRH 180
FTKSYNLLIH ERTHTDERPY TCDICHKAFR RQDHLRDHRY IHSKEKPFKC QECGKGFCQS 240
RTLAVHKTLH MQTSSPTAAS SAAKCSGETV ICGGTV 276

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologOSR2508692Q3T135Bos taurusPredictionMore>>
1:1 orthologOSR2481980E2QTV1Canis lupus familiarisPredictionMore>>
1:1 orthologOSR2102177997A0A452F9L8Capra hircusPredictionMore>>
1:1 orthologOSR2E5RH04Homo sapiensPredictionMore>>
1:1 orthologOsr2107587Q91ZD1CPOE12.5, E13.5, E14.5Mus musculusPublicationMore>>
1:1 orthologOSR2464306H2QWH9Pan troglodytesPredictionMore>>
1:1 orthologOSR2100155180F1S0N7Sus scrofaPredictionMore>>
1:1 orthologOsr2315039Q6AY34Rattus norvegicusPredictionMore>>
1:1 orthologosr2F1R0J1Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005634 nucleus
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding
GO:0060349 bone morphogenesis
GO:0002062 chondrocyte differentiation
GO:0042733 embryonic digit morphogenesis
GO:0035115 embryonic forelimb morphogenesis
GO:0035116 embryonic hindlimb morphogenesis
GO:0036023 embryonic skeletal limb joint morphogenesis
GO:0061029 eyelid development in camera-type eye
GO:0060322 head development
GO:0001823 mesonephros development
GO:0001656 metanephros development
GO:0042474 middle ear morphogenesis
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0042476 odontogenesis
GO:0033687 osteoblast proliferation
GO:0030501 positive regulation of bone mineralization
GO:0050679 positive regulation of epithelial cell proliferation
GO:0060021 roof of mouth development

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0479 Metal-binding
KW-1185 Reference proteome
KW-0862 Zinc
KW-0863 Zinc-finger

Interpro

InterPro ID InterPro Term
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

PROSITE

PROSITE ID PROSITE Term
PS00028 ZINC_FINGER_C2H2_1
PS50157 ZINC_FINGER_C2H2_2

Pfam

Pfam ID Pfam Term
PF00096 zf-C2H2