| Tag | Content |
|---|---|
| Uniprot ID | Q6AY34 |
| Entrez ID | 315039 |
| Genbank protein ID | AAH79211.1 |
| Genbank nucleotide ID | NM_001012118.1 |
| Ensembl protein ID | ENSRNOP00000014879 |
| Ensembl nucleotide ID | ENSRNOG00000011136 |
| Gene name | Protein odd-skipped-related 2 |
| Gene symbol | Osr2 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MGSKALPAPI PLHPSLQLTN YSFLQAVNTF PAAVDHLQGL YGLSAVQTMH MNHWTLGYPN 60 VHEITRSTIT EMAAAQGLVD ARFPFPALPF ATHLFHPKQG AIAHVLPALH KDRPRFDFAN 120 LAVAATQEDP PKMGDLSKLS PGLGSPISGL SKLTPDRKPS RGRLPSKTKK EFICKFCGRH 180 FTKSYNLLIH ERTHTDERPY TCDICHKAFR RQDHLRDHRY IHSKEKPFKC QECGKGFCQS 240 RTLAVHKTLH MQTSSPTAAS SAAKCSGETV ICGGTA 276 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | OSR2 | 508692 | Q3T135 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | OSR2 | 481980 | E2QTV1 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | OSR2 | 102177997 | A0A452F9L8 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | OSR2 | E5RH04 | Homo sapiens | Prediction | More>> | |||
| 1:1 ortholog | Osr2 | 107587 | Q91ZD1 | CPO | E12.5, E13.5, E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | OSR2 | 464306 | H2QWH9 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | OSR2 | 100155180 | F1S0N7 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | Osr2 | 315039 | Q6AY34 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | osr2 | F1R0J1 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific |
| GO:0001227 | DNA-binding transcription repressor activity, RNA polymerase II-specific |
| GO:0046872 | metal ion binding |
| GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding |
| GO:0043565 | sequence-specific DNA binding |
| GO:0060349 | bone morphogenesis |
| GO:0030154 | cell differentiation |
| GO:0002062 | chondrocyte differentiation |
| GO:0009792 | embryo development ending in birth or egg hatching |
| GO:0042733 | embryonic digit morphogenesis |
| GO:0035115 | embryonic forelimb morphogenesis |
| GO:0035116 | embryonic hindlimb morphogenesis |
| GO:0072498 | embryonic skeletal joint development |
| GO:0060272 | embryonic skeletal joint morphogenesis |
| GO:0036023 | embryonic skeletal limb joint morphogenesis |
| GO:0048704 | embryonic skeletal system morphogenesis |
| GO:0061029 | eyelid development in camera-type eye |
| GO:0060322 | head development |
| GO:0001823 | mesonephros development |
| GO:0001656 | metanephros development |
| GO:0042474 | middle ear morphogenesis |
| GO:0000122 | negative regulation of transcription by RNA polymerase II |
| GO:0042476 | odontogenesis |
| GO:0033687 | osteoblast proliferation |
| GO:0030501 | positive regulation of bone mineralization |
| GO:0008284 | positive regulation of cell population proliferation |
| GO:0050679 | positive regulation of epithelial cell proliferation |
| GO:2000543 | positive regulation of gastrulation |
| GO:0010628 | positive regulation of gene expression |
| GO:0045944 | positive regulation of transcription by RNA polymerase II |
| GO:0045893 | positive regulation of transcription, DNA-templated |
| GO:0048793 | pronephros development |
| GO:0060021 | roof of mouth development |
| GO:0001655 | urogenital system development |
| Pfam ID | Pfam Term |
|---|---|
| PF00096 | zf-C2H2 |