CleftGeneDB-Search

Gene: OSR2

Basic information

Tag	Content
Uniprot ID	E2QTV1
Entrez ID	481980
Genbank protein ID
Genbank nucleotide ID	XM_539101.5
Ensembl protein ID	ENSCAFP00000000717
Ensembl nucleotide ID	ENSCAFG00000000493
Gene name	Odd-skipped related transciption factor 2
Gene symbol	OSR2
Organism	Canis lupus familiaris
NCBI taxa ID	9615
Cleft type
Developmental stage
Data sources	Homology search
Reference
Functional description
Sequence	MGSKALPAPI PLHPSLQLTN YSFLQAVNTF PAAVDHLQGL YGLSAVQTMH MNHWTLGYPN 60 VHEITRSTIT EMAAAQGLVD ARFPFPALPF TTHLFHPKQG AIAHVLPALH KDRPRFDFAN 120 LAVAATQEDP PKMGDLTKLN PGLGSPISGL SKLTQDRKPS RGRLPSKTKK EFICKFCGRH 180 FTKSYNLLIH ERTHTDERPY TCDICHKAFR RQDHLRDHRY IHSKEKPFKC QECGKGFCQS 240 RTLAVHKTLH MQESPHKCPT CGRTFNQRSN LKTHLLTHTD IKPYSCEQCG KVFRRNCDLR 300 RHSLTHTPRQ DF 312

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

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Relation	Gene symbol	Entrez ID	UniProt ID	Cleft type	Developmental stage	Species	Evidence	Details
1:1 ortholog	Osr2	107587	Q91ZD1	CPO	E12.5, E13.5, E14.5	Mus musculus	Publication	More>>
1:1 ortholog	OSR2	508692	Q3T135			Bos taurus	Prediction	More>>
1:1 ortholog	OSR2	481980	E2QTV1			Canis lupus familiaris	Prediction	More>>
1:1 ortholog	OSR2	102177997	A0A452F9L8			Capra hircus	Prediction	More>>
1:1 ortholog	OSR2		E5RH04			Homo sapiens	Prediction	More>>
1:1 ortholog	OSR2	464306	H2QWH9			Pan troglodytes	Prediction	More>>
1:1 ortholog	OSR2	100155180	F1S0N7			Sus scrofa	Prediction	More>>
1:1 ortholog	Osr2	315039	Q6AY34			Rattus norvegicus	Prediction	More>>
1:1 ortholog	osr2		F1R0J1			Danio rerio	Prediction	More>>

Showing 1 to 9 of 9 entries

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Gene ontology

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GO ID	GO Term
GO:0000122	negative regulation of transcription by RNA polymerase II
GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001655	urogenital system development
GO:0001656	metanephros development
GO:0001823	mesonephros development
GO:0002062	chondrocyte differentiation
GO:0005634	nucleus
GO:0008284	positive regulation of cell population proliferation
GO:0009792	embryo development ending in birth or egg hatching
GO:0010628	positive regulation of gene expression
GO:0030501	positive regulation of bone mineralization
GO:0033687	osteoblast proliferation
GO:0035115	embryonic forelimb morphogenesis
GO:0035116	embryonic hindlimb morphogenesis
GO:0036023	embryonic skeletal limb joint morphogenesis
GO:0042474	middle ear morphogenesis
GO:0042476	odontogenesis
GO:0042733	embryonic digit morphogenesis
GO:0043565	sequence-specific DNA binding