| Tag | Content |
|---|---|
| Uniprot ID | E2QTV1 |
| Entrez ID | 481980 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_539101.5 |
| Ensembl protein ID | ENSCAFP00000000717 |
| Ensembl nucleotide ID | ENSCAFG00000000493 |
| Gene name | Odd-skipped related transciption factor 2 |
| Gene symbol | OSR2 |
| Organism | Canis lupus familiaris |
| NCBI taxa ID | 9615 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MGSKALPAPI PLHPSLQLTN YSFLQAVNTF PAAVDHLQGL YGLSAVQTMH MNHWTLGYPN 60 VHEITRSTIT EMAAAQGLVD ARFPFPALPF TTHLFHPKQG AIAHVLPALH KDRPRFDFAN 120 LAVAATQEDP PKMGDLTKLN PGLGSPISGL SKLTQDRKPS RGRLPSKTKK EFICKFCGRH 180 FTKSYNLLIH ERTHTDERPY TCDICHKAFR RQDHLRDHRY IHSKEKPFKC QECGKGFCQS 240 RTLAVHKTLH MQESPHKCPT CGRTFNQRSN LKTHLLTHTD IKPYSCEQCG KVFRRNCDLR 300 RHSLTHTPRQ DF 312 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | OSR2 | 508692 | Q3T135 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | OSR2 | 481980 | E2QTV1 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | OSR2 | 102177997 | A0A452F9L8 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | OSR2 | E5RH04 | Homo sapiens | Prediction | More>> | |||
| 1:1 ortholog | Osr2 | 107587 | Q91ZD1 | CPO | E12.5, E13.5, E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | OSR2 | 464306 | H2QWH9 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | OSR2 | 100155180 | F1S0N7 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | Osr2 | 315039 | Q6AY34 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | osr2 | F1R0J1 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific |
| GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding |
| GO:0043565 | sequence-specific DNA binding |
| GO:0060349 | bone morphogenesis |
| GO:0002062 | chondrocyte differentiation |
| GO:0009792 | embryo development ending in birth or egg hatching |
| GO:0042733 | embryonic digit morphogenesis |
| GO:0035115 | embryonic forelimb morphogenesis |
| GO:0035116 | embryonic hindlimb morphogenesis |
| GO:0036023 | embryonic skeletal limb joint morphogenesis |
| GO:0048704 | embryonic skeletal system morphogenesis |
| GO:0061029 | eyelid development in camera-type eye |
| GO:0060322 | head development |
| GO:0001823 | mesonephros development |
| GO:0001656 | metanephros development |
| GO:0042474 | middle ear morphogenesis |
| GO:0000122 | negative regulation of transcription by RNA polymerase II |
| GO:0042476 | odontogenesis |
| GO:0033687 | osteoblast proliferation |
| GO:0030501 | positive regulation of bone mineralization |
| GO:0008284 | positive regulation of cell population proliferation |
| GO:0050679 | positive regulation of epithelial cell proliferation |
| GO:0010628 | positive regulation of gene expression |
| GO:0045944 | positive regulation of transcription by RNA polymerase II |
| GO:0045893 | positive regulation of transcription, DNA-templated |
| GO:0060021 | roof of mouth development |
| GO:0001655 | urogenital system development |
| Pfam ID | Pfam Term |
|---|---|
| PF00096 | zf-C2H2 |