Gene: OSR2

Basic information

Tag Content
Uniprot ID Q3T135
Entrez ID 508692
Genbank protein ID AAI02144.1
Genbank nucleotide ID NM_001034328.2
Ensembl protein ID ENSBTAP00000017584
Ensembl nucleotide ID ENSBTAG00000013213
Gene name Protein odd-skipped-related 2
Gene symbol OSR2
Organism Bos taurus
NCBI taxa ID 9913
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MGSKALPAPI PLHPSLQLTN YSFLQAVNTF PAAVDHLQGL YGLSAVQTMH MNHWTLGYPN 60
VHEITRSTIT EMAAAQGLVD ARFSFPALPF TTHLFHPKQG AIAHVLPALH KDRPRFDFAN 120
LAVAATQEDP PKIADLSKLS PGLGSPISGL NKLTPDRKPS RGRLPSKTKK EFICKFCGRH 180
FTKSYNLLIH ERTHTDERPY TCDICHKAFR RQDHLRDHRY IHSKEKPFKC QECGKGFCQS 240
RTLAVHKTLH MQTSSPTAAS SAAKCSGETV ICGGTA 276

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologOSR2508692Q3T135Bos taurusPredictionMore>>
1:1 orthologOSR2481980E2QTV1Canis lupus familiarisPredictionMore>>
1:1 orthologOSR2102177997A0A452F9L8Capra hircusPredictionMore>>
1:1 orthologOSR2E5RH04Homo sapiensPredictionMore>>
1:1 orthologOsr2107587Q91ZD1CPOE12.5, E13.5, E14.5Mus musculusPublicationMore>>
1:1 orthologOSR2464306H2QWH9Pan troglodytesPredictionMore>>
1:1 orthologOSR2100155180F1S0N7Sus scrofaPredictionMore>>
1:1 orthologOsr2315039Q6AY34Rattus norvegicusPredictionMore>>
1:1 orthologosr2F1R0J1Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005634 nucleus
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0046872 metal ion binding
GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding
GO:0043565 sequence-specific DNA binding
GO:0060349 bone morphogenesis
GO:0002062 chondrocyte differentiation
GO:0009792 embryo development ending in birth or egg hatching
GO:0042733 embryonic digit morphogenesis
GO:0035115 embryonic forelimb morphogenesis
GO:0035116 embryonic hindlimb morphogenesis
GO:0036023 embryonic skeletal limb joint morphogenesis
GO:0048704 embryonic skeletal system morphogenesis
GO:0061029 eyelid development in camera-type eye
GO:0060322 head development
GO:0001823 mesonephros development
GO:0001656 metanephros development
GO:0042474 middle ear morphogenesis
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0042476 odontogenesis
GO:0033687 osteoblast proliferation
GO:0030501 positive regulation of bone mineralization
GO:0008284 positive regulation of cell population proliferation
GO:0050679 positive regulation of epithelial cell proliferation
GO:0010628 positive regulation of gene expression
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0045893 positive regulation of transcription, DNA-templated
GO:0060021 roof of mouth development
GO:0001655 urogenital system development

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0479 Metal-binding
KW-0539 Nucleus
KW-1185 Reference proteome
KW-0677 Repeat
KW-0862 Zinc
KW-0863 Zinc-finger

Interpro

InterPro ID InterPro Term
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

PROSITE

PROSITE ID PROSITE Term
PS00028 ZINC_FINGER_C2H2_1
PS50157 ZINC_FINGER_C2H2_2

Pfam

Pfam ID Pfam Term
PF00096 zf-C2H2