| Tag | Content |
|---|---|
| Uniprot ID | A0A452FQH4 |
| Entrez ID | 102177945 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_018059319.1 |
| Ensembl protein ID | ENSCHIP00000026568 |
| Ensembl nucleotide ID | ENSCHIG00000022853 |
| Gene name | Protein Wnt |
| Gene symbol | WNT10A |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | Ligand for members of the frizzled family of seven transmembrane receptors. |
| Sequence | MGSTHPCPWL RLRPRPQPRP ALCALFFLLL LAASVPRSAP NDILGLRLPQ EPVLNANTVC 60 LTLPGLSKRQ MEVCVRHPDV AASAIQGIQI AIHECQHQFR DQRWNCSSLE TRNKIPYESP 120 IFSRGFRESA FAYAISAAGV VHAVSNACAL GKLRACGCDA SRRGDEEAFR RKLHRLQLEA 180 LQRGKGLSHG VPEHPALPPA SPGLQDSWEW GGCSPDVGFG ERFSKDFLDS REPHRDIHAR 240 MRLHNNRVGR QAVMENMRRK CKCHGTSGSC QLKTCWQVTP EFRAVGALLR SRFHRATLIR 300 PHNRNSGQLE PGPAGAPSPA PGLPGPRRRA SPADLVYFEK SPDFCEREPR LDSAGTVGRL 360 CNKSSAGPDG CGSMCCGRGH NILRQTRSER CHCRFHWCCF VVCEECRITE WVSVCK 416 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | WNT10A | 537330 | F1MEW8 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | WNT10A | 488528 | E2RH98 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | WNT10A | 102177945 | A0A452FQH4 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | WNT10A | 80326 | Q9GZT5 | CPO,CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Wnt10a | 22409 | P70701 | E14.5 | Mus musculus | Prediction | More>> | |
| 1:1 ortholog | WNT10A | 459952 | H2QJF8 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | WNT10A | 100352839 | G1TAR3 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Wnt10a | 316527 | D3ZRW5 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | wnt10a | 30171 | B0V1G8 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005576 | extracellular region |
| GO:0048018 | receptor ligand activity |
| GO:0060070 | canonical Wnt signaling pathway |
| GO:0071560 | cellular response to transforming growth factor beta stimulus |
| GO:0031069 | hair follicle morphogenesis |
| GO:0014033 | neural crest cell differentiation |
| GO:0042476 | odontogenesis |
| GO:0010628 | positive regulation of gene expression |
| GO:0042487 | regulation of odontogenesis of dentin-containing tooth |
| GO:0048733 | sebaceous gland development |
| GO:0043586 | tongue development |
| PROSITE ID | PROSITE Term |
|---|---|
| PS00246 | WNT1 |
| Pfam ID | Pfam Term |
|---|---|
| PF00110 | wnt |