| Tag | Content |
|---|---|
| Uniprot ID | D3ZRW5 |
| Entrez ID | 316527 |
| Genbank protein ID | EDL75371.1 |
| Genbank nucleotide ID | NM_001108227.1 |
| Ensembl protein ID | ENSRNOP00000072067 |
| Ensembl nucleotide ID | ENSRNOG00000052510 |
| Gene name | Protein Wnt |
| Gene symbol | Wnt10a |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | Ligand for members of the frizzled family of seven transmembrane receptors. |
| Sequence | MGSAHPRPWL RLPPGPQPRP ELWALLFFLL LLAAAVPRSA PNDILGLRLP PEPVLNANTV 60 CLTLPGLSRR QMEVCVRHPD VAASAIQGIQ IAIHECQHQF RDQRWNCSSL ETRNKVPYES 120 PIFSRGFRES AFAYAIAAAG VVHAVSNACA LGKLKACGCD ASRRGDEEAF RRKLHRLQLD 180 ALQRGKGLSH GVPEHPAIPP ASPGLQDSWE WGGCSPDVGF GERFSKDFLD SREPHRDIHA 240 RMRLHNNRVG RQAVMENMRR KCKCHGTSGS CQLKTCWQVT PEFRTVGALL RNRFHRATLI 300 RPHNRNGGQL EPGLAGAPSP APGTPGLRRR ASHSDLVYFE KSPDFCEREP RLDSAGTVGR 360 LCNKSSTGPD SCGSMCCGRG HNILRQTRSE RCHCRFHWCC FVVCEECRIT EWVSVCK 417 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | WNT10A | 537330 | F1MEW8 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | WNT10A | 488528 | E2RH98 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | WNT10A | 102177945 | A0A452FQH4 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | WNT10A | 80326 | Q9GZT5 | CPO,CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Wnt10a | 22409 | P70701 | E14.5 | Mus musculus | Prediction | More>> | |
| 1:1 ortholog | WNT10A | 459952 | H2QJF8 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | WNT10A | 100352839 | G1TAR3 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Wnt10a | 316527 | D3ZRW5 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | wnt10a | 30171 | B0V1G8 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005615 | extracellular space |
| GO:0005109 | frizzled binding |
| GO:0048018 | receptor ligand activity |
| GO:0060070 | canonical Wnt signaling pathway |
| GO:0045165 | cell fate commitment |
| GO:0071560 | cellular response to transforming growth factor beta stimulus |
| GO:0048730 | epidermis morphogenesis |
| GO:0001942 | hair follicle development |
| GO:0031069 | hair follicle morphogenesis |
| GO:0014033 | neural crest cell differentiation |
| GO:0030182 | neuron differentiation |
| GO:0042476 | odontogenesis |
| GO:0010628 | positive regulation of gene expression |
| GO:0042487 | regulation of odontogenesis of dentin-containing tooth |
| GO:0048733 | sebaceous gland development |
| GO:0043588 | skin development |
| GO:0043586 | tongue development |
| GO:0016055 | Wnt signaling pathway |
| PROSITE ID | PROSITE Term |
|---|---|
| PS00246 | WNT1 |
| Pfam ID | Pfam Term |
|---|---|
| PF00110 | wnt |