Gene: wnt10a

Basic information

Tag Content
Uniprot ID B0V1G8
Entrez ID 30171
Genbank protein ID
Genbank nucleotide ID NM_130980.1
Ensembl protein ID ENSDARP00000005680
Ensembl nucleotide ID ENSDARG00000017155
Gene name Protein Wnt
Gene symbol wnt10a
Organism Danio rerio
NCBI taxa ID 7955
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description Ligand for members of the frizzled family of seven transmembrane receptors.
Sequence
MSSHDISWHS PASVYFSSDL DVKRIAGKLR GCWTDLLLRQ ESCCERVLQK SSSSMDYFLF 60
RLFCSLALAS LLVQRADSNE ILGLKIPFDP ILNANTVCLT LPGLTKKQLD VCMRNPDVTA 120
SAIQGIQIAI HECQHQFRGH RWNCSSLETR NKIPYESVVF SRGFRESAFA YAIAAAGVVH 180
AVSNACAMGK LKACGCDEKR RGDEEAFRIK LNRLQLEAIN RGKGMVHGVM EHFPAEALGP 240
QDSWEWGGCS PNVEYGERFS KDFLDSRETY RDIHSRMRLH NNRVGRQVVV DHMRRKCKCH 300
GTSGSCQLKT CWQVTPEFRT VGSLLKERFN VATLIKAHNR NTGQVENAHH THRRRANIND 360
LVYFEKSPDF CERDLGSDSA GTQGRICNKT SQGMDNCESL CCGRGHNILQ QTRSERCNCK 420
FHWCCYVVCE ECRITEWVSV CK 442

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologWNT10A537330F1MEW8Bos taurusPredictionMore>>
1:1 orthologWNT10A488528E2RH98Canis lupus familiarisPredictionMore>>
1:1 orthologWNT10A102177945A0A452FQH4Capra hircusPredictionMore>>
1:1 orthologWNT10A80326Q9GZT5CPO,CL/PHomo sapiensPublicationMore>>
1:1 orthologWnt10a22409P70701E14.5Mus musculusPredictionMore>>
1:1 orthologWNT10A459952H2QJF8Pan troglodytesPredictionMore>>
1:1 orthologWNT10A100352839G1TAR3Oryctolagus cuniculusPredictionMore>>
1:1 orthologWnt10a316527D3ZRW5Rattus norvegicusPredictionMore>>
1:1 orthologwnt10a30171B0V1G8Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005576 extracellular region
GO:0005102 signaling receptor binding
GO:0007275 multicellular organism development
GO:0016055 Wnt signaling pathway

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0217 Developmental protein
KW-1015 Disulfide bond
KW-0272 Extracellular matrix
KW-0325 Glycoprotein
KW-0449 Lipoprotein
KW-1185 Reference proteome
KW-0964 Secreted
KW-0732 Signal
KW-0879 Wnt signaling pathway

Interpro

InterPro ID InterPro Term
IPR005817 Wnt
IPR013302 Wnt10
IPR043158 Wnt_C
IPR018161 Wnt_CS

PROSITE

PROSITE ID PROSITE Term
PS00246 WNT1

Pfam

Pfam ID Pfam Term
PF00110 wnt