| Tag | Content |
|---|---|
| Uniprot ID | A0A452FRV1 |
| Entrez ID | 102170271 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_018051054.1 |
| Ensembl protein ID | ENSCHIP00000027049 |
| Ensembl nucleotide ID | ENSCHIG00000023154 |
| Gene name | Uncharacterized protein |
| Gene symbol | RYK |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MRGTAGPGPP GQGRLPGTRG LKAPPPPLLL LLALLPLLPT PGAAAAPASR PPALPPAAAG 60 PSVSLYLSED EVRRLIGLDA ELYYVRNDLI SHYALSFNLL VPSETNFLHF TWHAKSKVEY 120 KLGFQVDNFV AMDMPQVNIS AQGEVPRTLS VFRVELSCTG KVDSEVMILM QLNLTVNSSK 180 NFTVLNFKRR KMCYKKLEEV KTSALDKNTS RTIYDPVHAA PTTSTRVFYI SVGVCCAVIF 240 LVAIILAVLH LHSMKRIELD DSISASSSSQ GLSQPSTQTT QYLRADTPNN ATPITSSSGY 300 PTLRIEKNDL RSVTLLEAKA KVKDIAISRE RITLKDVLQE GTFGRIFHGI LVDEKDPNKE 360 KQTFVKTVKD QASEIQVTMM LTESCKLRGL HHRNLLPITN VCIEEGEKPM VILPYMNWGN 420 LKLFLRQCKL VEANNPQAIS QQDLVHMAIQ IACGMSYLAR REVIHKDLAA RNCVIDDTLQ 480 VKITDNALSR DLFPMDYHCL GDNENRPVRW MALESLVNNE FSSASDVWAF GVTLWELMTL 540 GQTPYVDIDP FEMAAYLKDG YRIAQPINCP DELFAVMACC WALDPEERPK FQQLVQCLTE 600 FHAALGAYV 609 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | RYK | 102170271 | A0A452FRV1 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | RYK | 6259 | P34925 | CPO,CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Ryk | 20187 | Q01887 | CPO | E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | RYK | 470931 | H2QNE9 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | Ryk | F1LQR5 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | ryk | 558502 | A2RRV7 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005737 | cytoplasm |
| GO:0016021 | integral component of membrane |
| GO:0005634 | nucleus |
| GO:0005886 | plasma membrane |
| GO:0005524 | ATP binding |
| GO:0005109 | frizzled binding |
| GO:0004672 | protein kinase activity |
| GO:0042813 | Wnt-activated receptor activity |
| GO:0017147 | Wnt-protein binding |
| GO:0036518 | chemorepulsion of dopaminergic neuron axon |
| GO:0071679 | commissural neuron axon guidance |
| GO:0022038 | corpus callosum development |
| GO:1904948 | midbrain dopaminergic neuron differentiation |
| GO:0048843 | negative regulation of axon extension involved in axon guidance |
| GO:1904938 | planar cell polarity pathway involved in axon guidance |
| GO:0043410 | positive regulation of MAPK cascade |
| GO:0048705 | skeletal system morphogenesis |