| Tag | Content |
|---|---|
| Uniprot ID | A0A452FXM0 |
| Entrez ID | 102179422 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_018052772.1 |
| Ensembl protein ID | ENSCHIP00000029175 |
| Ensembl nucleotide ID | ENSCHIG00000024392 |
| Gene name | Uncharacterized protein |
| Gene symbol | SIM2 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MKEKSKNAAK TRREKENGEF YELAKLLPLP SAITSQLDKA SIIRLTTSYL KMRAVFPEGL 60 GDAWGQPSRA GPLDSVAKEL GSHLLQTLDG FVFVVASDGK IMYISETASV HLGLSQVELT 120 GNSIYEYIHP SDHDEMTAVL AAHQPLHHHL LQEYEIERSF FLRMKCVLAK RNAGLTCSGY 180 KVIHCSGYLK IRQYMLDMSL YDSCYQIVGL VAVGQSLPPS AITEIKLHSN MFMFRASLDL 240 KLIFLDSRVT ELTGYEPQDL IEKTLYHHVH GCDVFHLRYA HHLLLVKGQV TTKYYRLLSK 300 LGGWVWVQSY ATVVHNSRSS RPHCIVSVNY VLTDIEYKEL QLSLDQVSTS KSQDSWRTTL 360 PTSQETRKLA KPKNTKMKTK LRANPYPTQQ YGSFQMDKLE CSQLGSWRAS PPAHGPAPPE 420 QQLHSEGGDL LYAPSYGLPF SYHYGPFPLD SHVFSSKKPV LPAKFGQPQG PPCEVARFLL 480 SALPAGSECQ WRYASPLVPG SPSPAKSLSE PPVNPARHSL MPNYEAPAAA RRFGEDTAPP 540 PPPSFPSCGH YREEPAPGPA KAARQAARDG ARLALGRAPP ECCAPPAPAP PGAPAQLPLV 600 LLNYHRVLAR RGPLGGAAPG APGLACGPGA PEAAGGALRA RAPGPVGPAA APPPGAPRPH 660 YLGASVIITN GR 672 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | SIM2 | A0A5F4C0N9 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | SIM2 | 102179422 | A0A452FXM0 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | SIM2 | 6493 | Q14190 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Sim2 | 20465 | Q61079 | CPO | E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | SIM2 | 474107 | A0A2I3TNB0 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | SIM2 | I3LA51 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Sim2 | 304071 | D4AA36 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0016604 | nuclear body |
| GO:0003677 | DNA binding |
| GO:0003700 | DNA-binding transcription factor activity |
| GO:0046982 | protein heterodimerization activity |
| GO:0009880 | embryonic pattern specification |
| GO:0030324 | lung development |
| GO:0000122 | negative regulation of transcription by RNA polymerase II |