| Tag | Content |
|---|---|
| Uniprot ID | A0A5F4C0N9 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSCAFP00000047785 |
| Ensembl nucleotide ID | ENSCAFG00000009686 |
| Gene name | SIM bHLH transcription factor 2 |
| Gene symbol | SIM2 |
| Organism | Canis lupus familiaris |
| NCBI taxa ID | 9615 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MKEKSKNAAK TRREKENGEF YELAKLLPLP SAITSQLDKA SIIRLTTSYL KMRAVFPEGL 60 GDAWGQPCRA GPLDSVAKEL GSHLLQTLDG FVFVVASDGK IMYISETASV HLGLSQVELT 120 GNSIYEYIHP SDHDEMTAVL AAHQPLHHHL LQEYEIERSF FLRMKCVLAK RNAGLTCSGY 180 KVIHCSGYLK IRQYMLDMSL YDSCYQIVGL VAVGQSLPPS AITEIKLHSN MFMFRASLDL 240 KLIFLDSRVT ELTGYEPQDL IEKTLYHHVH GCDVFHLRYA HHLLLVKGQV TTKYYRLLSK 300 LGGWVWVQSY ATIVHNSRSS RPHCIVSVNY VLTDIEYKEL QLSLDQASTS KSQDSWRTAL 360 STSQETRKLA KPKNTKMKTK LRTNPYPPQQ YSSFQMDKLE CSQLANWRAS PPATAPAPPE 420 QQLHSESSDL LYAPSYSLPF SYHYGHFPLD SHVFSSKKPM LPAKFGQPQG SPCEVARFFL 480 STLPAGGECQ WHYANPLVPS SPSPAKNLSE PPVNSARHGL VPNYEGRSCL HEGRGRDREQ 540 WRWVADGKKI LTLGADFSFF CS 562 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | SIM2 | A0A5F4C0N9 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | SIM2 | 102179422 | A0A452FXM0 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | SIM2 | 6493 | Q14190 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Sim2 | 20465 | Q61079 | CPO | E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | SIM2 | 474107 | A0A2I3TNB0 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | SIM2 | I3LA51 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Sim2 | 304071 | D4AA36 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0003677 | DNA binding |
| GO:0003700 | DNA-binding transcription factor activity |
| GO:0046983 | protein dimerization activity |