| Tag | Content |
|---|---|
| Uniprot ID | A0A452G6W1 |
| Entrez ID | 102188948 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_018053357.1 |
| Ensembl protein ID | ENSCHIP00000032334 |
| Ensembl nucleotide ID | ENSCHIG00000026337 |
| Gene name | Uncharacterized protein |
| Gene symbol | MTHFD1L |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MSALLPLVLR RLARPQHPGP PRRLPSLCRP SSSGGSGCGS GEGLLGQQRL PDTQAGSSRG 60 PSSPAPPARD SIVREIIQNS KEVLSLLQEK TPTFKPVLAV IQAGDDNLMQ EVNQNLAEEA 120 GLNITHICLP AESGEDEIID EILKINEDSR VHGLALQIAE TSLSSKILNA LKPEKDVDGL 180 TDVNLGKLVR GDAHECFISP VARAVIELLE KSGVSLDGKK ILVIGAHGSL EATLQCLFQR 240 KGSMTMSSQW KTPQLQGKLQ EADIVVLGSP KPEEIPLSWI QLGTTVFNCS HDFLSGKAAC 300 VSPGVHGISP IAEDVSLLAA ALRIQNMVSS GRRWLREQQH RRWRLHCLKL QPLSPVPSDI 360 EISRAQTPKA VEILAKEIGL FADEIEIYGK SKAKVRLSLL ERLKDQADGK YVLVAGITPT 420 PLGEGKSTVT IGLVQALTAH LNVNSFACLR QPSQGPTFGV KGGAAGGGYA QVIPMEEFNL 480 HLTGDIHAIT AANNLLAAAI DARILHENTQ TDKALYNRLV PSVNGVREFS KIQLARLKRL 540 GISKTDPSAL TEEEMRKFAR LDIDPSTITW QRVVDTNDRF LRKITVGQAS TEKGCSRQAQ 600 FDIAVASEIM AVLALTDSLA DMKERLGRMV VASDKNGQPV TADDLGVTGA LTVLMKDAIK 660 PNLMQTLEGT PVFVHAGPFA NIAHGNSSVL ADKIALKLVG EGGFVVTEAG FGADIGMEKF 720 FNIKCRASGL VPNVVVLVAT VRALKMHGGG PSVTAGVPLK KEYTEENLQL VADGCCNLEK 780 QIQIAQLFGV PVVVALNVFK TDTRAEIDLV CELAKRAGAF NAVPCYHWSI GGKGSVDLAW 840 AVREAASKES RFQFLYDVQL PIVEKIRTIA QSVYGAKDIE LSPEAQSKID RYTEQGFGNL 900 PICMAKTHLS LSHQPDKKGV PKGFILPISD VRASIGAGFI YPLVGTMSTM PGLPTRPCFY 960 DIDLDTETEQ VKGLF 975 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | MTHFD1L | 102188948 | A0A452G6W1 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | MTHFD1L | 25902 | B7ZM99 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Mthfd1l | 270685 | Q3V3R1 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | H2QTW9 | Pan troglodytes | Prediction | More>> | ||||
| 1:1 ortholog | MTHFD1L | F1S7V9 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Mthfd1l | 361472 | B2GUZ3 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | mthfd1l | 100034522 | F1QQ79 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005739 | mitochondrion |
| GO:0005524 | ATP binding |
| GO:0004329 | formate-tetrahydrofolate ligase activity |
| GO:0004488 | methylenetetrahydrofolate dehydrogenase (NADP+) activity |
| GO:0048702 | embryonic neurocranium morphogenesis |
| GO:0048703 | embryonic viscerocranium morphogenesis |
| GO:0001843 | neural tube closure |
| Keyword ID | Keyword Term |
|---|---|
| KW-1185 | Reference proteome |