| Tag | Content |
|---|---|
| Uniprot ID | F1S7V9 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSSSCP00000004421 |
| Ensembl nucleotide ID | ENSSSCG00000004092 |
| Gene name | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like |
| Gene symbol | MTHFD1L |
| Organism | Sus scrofa |
| NCBI taxa ID | 9823 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | PLSLSHIFNL FLGRNLQPLG KGCQSPDQGL NPGGREVIQN SKEVLSLLQE KNPAFKPVLA 60 VIQAGEDNLM QEINQKLAEE AGLNITHICL PADSSEDEII DEILKINEDS RVHGLALQIS 120 ETSFSSKILH ALKPEKDVDG VTDVNLGKLV RGDAHDCFVS PVARAVIELL EKSGVNLDGR 180 KILVIGAHGS LEATLQCLFQ RKGSMTMSSQ WKAPQLQSKL HEADVVIFGS PKPEEVPLSW 240 IQQGTAVLNC SHDFLSGKWL QIGSPGIHGH SLIAEDVSLL AAALRIQNMV GSGRRWLREQ 300 QYRRWKLHCL KLQPLSPVPS DIEISRAQTP KAVDVLAKEI GLLEDEIEIY GRSKAKVRLS 360 LLERLKDQAD GKYVLVAGIT PTPLGEGKST VTIGLVQAMT AHLNVNSFAC LRQPSQGPTF 420 GVKGGAAGGG YAQVIPMEEF NLHLTGDIHA ITAANNLLAA AIDTRILHEN TQTDKALYNR 480 LVPSVNGIRE FSKIQLARLK KLGINKTDPS ALTEDEMRKF ARLDIDPATI TWQRVLDTND 540 RFLRKITLGR GTQRKAQFDI AVASEIMAVL ALTDSLKDMK ERLGRMVVAS DKNGQPVTAD 600 DLGVTGALTV LMKDAIKPNL MQTLEGTPVF VHAGPFANIA HGNSSVLADK IALKLVGEEG 660 FVVTEAGFGA DIGMEKFFNI KCRASGLVPN VVVLVATVRA LKMHGGGPSV TAGVPLKKEY 720 TEENLQLVAD GCCNLKKQIQ IAQLFGVPVV VALNVFKTDT RAEIDLVCEL AKQAGAFDAV 780 PCYHWSVGGK GSVDLAWAVS EAAHKGSRFQ FLYDVQLPIV EKIRTIAQAV YGARDIELSS 840 EAQSKIDRYT EQGFGNLPIC MAKTHLSLSH QPDKKGVPKD FILPITDVRA SIGAGFIYPL 900 VGTMSTMPGL PTRPCFYDID LDTETEQVQG LF 932 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | MTHFD1L | 102188948 | A0A452G6W1 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | MTHFD1L | 25902 | B7ZM99 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Mthfd1l | 270685 | Q3V3R1 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | H2QTW9 | Pan troglodytes | Prediction | More>> | ||||
| 1:1 ortholog | MTHFD1L | F1S7V9 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Mthfd1l | 361472 | B2GUZ3 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | mthfd1l | 100034522 | F1QQ79 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005524 | ATP binding |
| GO:0004329 | formate-tetrahydrofolate ligase activity |
| GO:0004488 | methylenetetrahydrofolate dehydrogenase (NADP+) activity |