Gene: PORCN

Basic information

Tag Content
Uniprot ID A0A5F4BU92
Entrez ID 480903
Genbank protein ID
Genbank nucleotide ID XM_005641316.2; XM_003435507.3;
Ensembl protein ID ENSCAFP00000045416
Ensembl nucleotide ID ENSCAFG00000015435
Gene name Porcupine O-acyltransferase
Gene symbol PORCN
Organism Canis lupus familiaris
NCBI taxa ID 9615
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MATFSRQEFF QQLLQGCLLP TAQQGLDQIW LLLAICLACR LLWRLGLPSY LKHASTVAGG 60
FFSLYHFFQL HMVWVVLLSL LCYLVLFLCR HSSHRGVFLS VTILIYLLMG EMHMVDTVTW 120
HKMRGAQMIV AMKAVSLGFD LDRGEVGAVP SPMEFMGYLY FVGTIVFGPW ISFHSYLQAV 180
QGRPLSRRWL QKVARSLALA LLCLVLSTCV GPYLFPYFIP LDGDRLLRNK KRKARGTMVR 240
WLRAYESAVS FHFSNYFVGF LSEATATLAG AGFTEEKDHL EWDLTVSKPL NVELPRSMVE 300
VVTSWNLPMS YWLNNYVFKN ALRLGTFSAV LVTYAASALL HGFSFHLAAV LLSLAFITYV 360
EHVLRKRLAR ILSACVLSKR CPPNCSHQHR LGLGVRVLNL LFGALAIFHL AYLGSLFDVD 420
VDDTTEEQGY GMAYTVHKWS ELSWASHWVT FGCWIFYRLI G 461

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologPORCN540373A7MB52Bos taurusPredictionMore>>
1:1 orthologPORCN480903A0A5F4BU92Canis lupus familiarisPredictionMore>>
1:1 orthologPORCN102177509A0A452EU12Capra hircusPredictionMore>>
1:1 orthologPORCN64840Q9H237Homo sapiensPredictionMore>>
1:1 orthologPorcn53627Q9JJJ7CPOMus musculusPublicationMore>>
1:1 orthologPORCNA0A2J8IQT0Pan troglodytesPredictionMore>>
1:1 orthologPORCN100627921A0A287B2I9Sus scrofaPredictionMore>>
1:1 orthologPorcn317368D3ZVQ3Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0016021 integral component of membrane

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0472 Membrane
KW-1185 Reference proteome
KW-0812 Transmembrane
KW-1133 Transmembrane helix

Interpro

InterPro ID InterPro Term
IPR004299 MBOAT_fam

PROSITE

PROSITE ID PROSITE Term

Pfam

Pfam ID Pfam Term
PF03062 MBOAT