| Tag | Content |
|---|---|
| Uniprot ID | D3ZVQ3 |
| Entrez ID | 317368 |
| Genbank protein ID | |
| Genbank nucleotide ID | NM_001173355.1 |
| Ensembl protein ID | ENSRNOP00000006491 |
| Ensembl nucleotide ID | ENSRNOG00000004819 |
| Gene name | Porcupine O-acyltransferase |
| Gene symbol | Porcn |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MATFSRQEFF QQLLQGCLLP TVQQGLDQIW LLLTICFACR LLWRLGLPSY LKHASTVAGG 60 FFSLYHFFQL HMVWVVLLSL LCYLVLFLCR HSSHRGVFLS VTILIYLLMG EMHMVDTVTW 120 HKMRGAQMIV AMKAVSLGFD LDRGEVGAVP SPVEFMGYLY FVGTIVFGPW ISFHSYLQAV 180 QGRPLSRRWL KKVARSLALA LLCLVLSTCV GPYLFPYFIP LDGDRLLRNK KRKARGTMVR 240 WLRAYESAVS FHFSNYFVGF LSEATATLAG AGFTEEKDHL EWDLTVSRPL NVELPRSMVE 300 VVTSWNLPMS YWLNNYVFKN ALRLGTFSAV LVTYAASALL HGFSFHLAAV LLSLAFITYV 360 EHVLRKRLAQ ILSACILSKR CLPDCSHRHR LGLGVRALNL LFGALAVFHL AYLGSLFDVD 420 VDDTTEEQGY GMAYTVHKWS ELSWASHWVT FGCWIFYRLI G 461 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | PORCN | 540373 | A7MB52 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | PORCN | 480903 | A0A5F4BU92 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | PORCN | 102177509 | A0A452EU12 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | PORCN | 64840 | Q9H237 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Porcn | 53627 | Q9JJJ7 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | PORCN | A0A2J8IQT0 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | PORCN | 100627921 | A0A287B2I9 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | Porcn | 317368 | D3ZVQ3 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0032281 | AMPA glutamate receptor complex |
| GO:0005783 | endoplasmic reticulum |
| GO:0098978 | glutamatergic synapse |
| GO:0030176 | integral component of endoplasmic reticulum membrane |
| GO:1990698 | palmitoleoyltransferase activity |
| GO:0017147 | Wnt-protein binding |
| GO:0060070 | canonical Wnt signaling pathway |
| GO:0009100 | glycoprotein metabolic process |
| GO:0006497 | protein lipidation |
| GO:0045234 | protein palmitoleylation |
| GO:0099072 | regulation of postsynaptic membrane neurotransmitter receptor levels |
| GO:0016055 | Wnt signaling pathway |
| InterPro ID | InterPro Term |
|---|---|
| IPR004299 | MBOAT_fam |
| Pfam ID | Pfam Term |
|---|---|
| PF03062 | MBOAT |