| Tag | Content |
|---|---|
| Uniprot ID | A7MB52 |
| Entrez ID | 540373 |
| Genbank protein ID | AAI51342.1 |
| Genbank nucleotide ID | NM_001101208.1 |
| Ensembl protein ID | ENSBTAP00000012232 |
| Ensembl nucleotide ID | ENSBTAG00000009282 |
| Gene name | PORCN protein |
| Gene symbol | PORCN |
| Organism | Bos taurus |
| NCBI taxa ID | 9913 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MATFSRQEFF QQLLQGCLLP TAQQGLDQIW LLLAICLACR LLWRLGLPSY LKHASTVAGG 60 FFSLYHFFQL HMVWVVLLSL LCYLVLFLCR HSSHRGVFLS VTILIYLLMG EMHMVDTVTW 120 HKMRGAQMIV AMKAVSLGFD LDRGEVGAVP SPVEFMGYLY FVGTIVFGPW ISFHSYLQAV 180 QGHPLSRRWL QKVARSLALA LLCLVLSTCV GPYLFPYFIP LDGDRLLRKW LRAYESAVSF 240 HFSNYFVGFL SEATATLAGA GFTEEKDHLE WDLTVSKPLN VELPRSMVEV VTSWNLPMSY 300 WLNNYVFKNA LHLGTFSAVL VTYAASALLH GFSFHLAAVL LSLAFITYVE HVLRKRLARI 360 LSACVLSKRC PPDCSHQHRL GLGVRALNLF FGALAIFHLA YLGSLFDVDV DDTTEEQGYG 420 MAYTVHKWSE LSWASHWVTF GCWIFYRLIG |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | PORCN | 540373 | A7MB52 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | PORCN | 480903 | A0A5F4BU92 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | PORCN | 102177509 | A0A452EU12 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | PORCN | 64840 | Q9H237 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Porcn | 53627 | Q9JJJ7 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | PORCN | A0A2J8IQT0 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | PORCN | 100627921 | A0A287B2I9 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | Porcn | 317368 | D3ZVQ3 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0032281 | AMPA glutamate receptor complex |
| GO:0098978 | glutamatergic synapse |
| GO:0030176 | integral component of endoplasmic reticulum membrane |
| GO:1990698 | palmitoleoyltransferase activity |
| GO:0017147 | Wnt-protein binding |
| GO:0060070 | canonical Wnt signaling pathway |
| GO:0009100 | glycoprotein metabolic process |
| GO:0045234 | protein palmitoleylation |
| GO:0099072 | regulation of postsynaptic membrane neurotransmitter receptor levels |
| InterPro ID | InterPro Term |
|---|---|
| IPR004299 | MBOAT_fam |
| Pfam ID | Pfam Term |
|---|---|
| PF03062 | MBOAT |