Gene: PORCN

Basic information

Tag Content
Uniprot ID A7MB52
Entrez ID 540373
Genbank protein ID AAI51342.1
Genbank nucleotide ID NM_001101208.1
Ensembl protein ID ENSBTAP00000012232
Ensembl nucleotide ID ENSBTAG00000009282
Gene name PORCN protein
Gene symbol PORCN
Organism Bos taurus
NCBI taxa ID 9913
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MATFSRQEFF QQLLQGCLLP TAQQGLDQIW LLLAICLACR LLWRLGLPSY LKHASTVAGG 60
FFSLYHFFQL HMVWVVLLSL LCYLVLFLCR HSSHRGVFLS VTILIYLLMG EMHMVDTVTW 120
HKMRGAQMIV AMKAVSLGFD LDRGEVGAVP SPVEFMGYLY FVGTIVFGPW ISFHSYLQAV 180
QGHPLSRRWL QKVARSLALA LLCLVLSTCV GPYLFPYFIP LDGDRLLRKW LRAYESAVSF 240
HFSNYFVGFL SEATATLAGA GFTEEKDHLE WDLTVSKPLN VELPRSMVEV VTSWNLPMSY 300
WLNNYVFKNA LHLGTFSAVL VTYAASALLH GFSFHLAAVL LSLAFITYVE HVLRKRLARI 360
LSACVLSKRC PPDCSHQHRL GLGVRALNLF FGALAIFHLA YLGSLFDVDV DDTTEEQGYG 420
MAYTVHKWSE LSWASHWVTF GCWIFYRLIG

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologPORCN540373A7MB52Bos taurusPredictionMore>>
1:1 orthologPORCN480903A0A5F4BU92Canis lupus familiarisPredictionMore>>
1:1 orthologPORCN102177509A0A452EU12Capra hircusPredictionMore>>
1:1 orthologPORCN64840Q9H237Homo sapiensPredictionMore>>
1:1 orthologPorcn53627Q9JJJ7CPOMus musculusPublicationMore>>
1:1 orthologPORCNA0A2J8IQT0Pan troglodytesPredictionMore>>
1:1 orthologPORCN100627921A0A287B2I9Sus scrofaPredictionMore>>
1:1 orthologPorcn317368D3ZVQ3Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0032281 AMPA glutamate receptor complex
GO:0098978 glutamatergic synapse
GO:0030176 integral component of endoplasmic reticulum membrane
GO:1990698 palmitoleoyltransferase activity
GO:0017147 Wnt-protein binding
GO:0060070 canonical Wnt signaling pathway
GO:0009100 glycoprotein metabolic process
GO:0045234 protein palmitoleylation
GO:0099072 regulation of postsynaptic membrane neurotransmitter receptor levels

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0472 Membrane
KW-1185 Reference proteome
KW-0812 Transmembrane
KW-1133 Transmembrane helix

Interpro

InterPro ID InterPro Term
IPR004299 MBOAT_fam

PROSITE

PROSITE ID PROSITE Term

Pfam

Pfam ID Pfam Term
PF03062 MBOAT