| Tag | Content |
|---|---|
| Uniprot ID | A0A5F4DKS6 |
| Entrez ID | 480017 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_537140.4 |
| Ensembl protein ID | ENSCAFP00000065543 |
| Ensembl nucleotide ID | ENSCAFG00000012038 |
| Gene name | Hedgehog acyltransferase |
| Gene symbol | HHAT |
| Organism | Canis lupus familiaris |
| NCBI taxa ID | 9615 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MLPWWELSFY LCASLGFHLY SFYEVYKASR EHEEELDRQF DLEIGTLFGG LKKDPNDFEW 60 SFWMEWGKQR LVRFLFGHMV VSQMANVLAR KHRPWILGAY GMWASWCVLG AHGTAIIFLH 120 TLISFCVAQL RSLALTWLCS LFLLSTLRLQ DVEEVKRGWY QTENEYYLLQ FTLTVRCLYY 180 TSFSLEFCWQ QMPNGHSFYS FPWLVAYVFY YPVFHNGPIL SFPEFIAKVQ QQEYCSLKSN 240 LSAFAVGLGR LLCYWWLAEL MVHLMYMHAI YSSASLLKAV SCWTLGGLAL AHVLFFYLKY 300 LVLFGVPALL MRLDGLTPPP LPRCVSTMFS FTGMWRYFDV GLHDFLIRYV YIPVGGSQHG 360 LLGTLFSTAV TFAFVSFWHG GYDYLWCWAA LNWLGVTVEN VVQRLVRTPC IQDSVIQFLS 420 PQARRRFHAA LASCSTSMLI LSNLVFLGGS QVGKIYWNRI FIQGWPYVTL SVLGFLYCYS 480 HVGIAWSQTY SVD 493 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | HHAT | 480017 | A0A5F4DKS6 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | HHAT | 102188788 | A0A452E3S0 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | HHAT | 55733 | Q5VTY9 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Hhat | 226861 | Q8BMT9 | CLP | Mus musculus | Publication | More>> | |
| 1:1 ortholog | HHAT | 469670 | H2Q128 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | HHAT | F1S2U1 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Hhat | M0R7X5 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | hhat | 560334 | F8W2J4 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0016021 | integral component of membrane |
| GO:0016409 | palmitoyltransferase activity |
| GO:0018345 | protein palmitoylation |
| GO:0007224 | smoothened signaling pathway |
| Pfam ID | Pfam Term |
|---|---|
| PF03062 | MBOAT |