Gene: HHAT

Basic information

Tag Content
Uniprot ID A0A5F4DKS6
Entrez ID 480017
Genbank protein ID
Genbank nucleotide ID XM_537140.4
Ensembl protein ID ENSCAFP00000065543
Ensembl nucleotide ID ENSCAFG00000012038
Gene name Hedgehog acyltransferase
Gene symbol HHAT
Organism Canis lupus familiaris
NCBI taxa ID 9615
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MLPWWELSFY LCASLGFHLY SFYEVYKASR EHEEELDRQF DLEIGTLFGG LKKDPNDFEW 60
SFWMEWGKQR LVRFLFGHMV VSQMANVLAR KHRPWILGAY GMWASWCVLG AHGTAIIFLH 120
TLISFCVAQL RSLALTWLCS LFLLSTLRLQ DVEEVKRGWY QTENEYYLLQ FTLTVRCLYY 180
TSFSLEFCWQ QMPNGHSFYS FPWLVAYVFY YPVFHNGPIL SFPEFIAKVQ QQEYCSLKSN 240
LSAFAVGLGR LLCYWWLAEL MVHLMYMHAI YSSASLLKAV SCWTLGGLAL AHVLFFYLKY 300
LVLFGVPALL MRLDGLTPPP LPRCVSTMFS FTGMWRYFDV GLHDFLIRYV YIPVGGSQHG 360
LLGTLFSTAV TFAFVSFWHG GYDYLWCWAA LNWLGVTVEN VVQRLVRTPC IQDSVIQFLS 420
PQARRRFHAA LASCSTSMLI LSNLVFLGGS QVGKIYWNRI FIQGWPYVTL SVLGFLYCYS 480
HVGIAWSQTY SVD 493

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologHHAT480017A0A5F4DKS6Canis lupus familiarisPredictionMore>>
1:1 orthologHHAT102188788A0A452E3S0Capra hircusPredictionMore>>
1:1 orthologHHAT55733Q5VTY9Homo sapiensPredictionMore>>
1:1 orthologHhat226861Q8BMT9CLPMus musculusPublicationMore>>
1:1 orthologHHAT469670H2Q128Pan troglodytesPredictionMore>>
1:1 orthologHHATF1S2U1Sus scrofaPredictionMore>>
1:1 orthologHhatM0R7X5Rattus norvegicusPredictionMore>>
1:1 orthologhhat560334F8W2J4Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0016021 integral component of membrane
GO:0016409 palmitoyltransferase activity
GO:0018345 protein palmitoylation
GO:0007224 smoothened signaling pathway

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0472 Membrane
KW-1185 Reference proteome
KW-0812 Transmembrane
KW-1133 Transmembrane helix

Interpro

InterPro ID InterPro Term
IPR032981 HHAT
IPR004299 MBOAT_fam

PROSITE

PROSITE ID PROSITE Term

Pfam

Pfam ID Pfam Term
PF03062 MBOAT