| Tag | Content |
|---|---|
| Uniprot ID | F8W2J4 |
| Entrez ID | 560334 |
| Genbank protein ID | |
| Genbank nucleotide ID | NM_001114890.2 |
| Ensembl protein ID | ENSDARP00000124707 |
| Ensembl nucleotide ID | ENSDARG00000074428 |
| Gene name | Hedgehog acyltransferase |
| Gene symbol | hhat |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MTPKWELVSL PRWEMVAYWI LSFSSHFYSF YQLHSFSKEH EVSLDKEVQL ERGFLLWGFK 60 KDPTDFEWSF WNEWAWRSLL WSLIGHAVVS RLAYYYLPQY RLAVFAMYGL ISAGWILGVR 120 GVIVLMLHLS ISLVVAQLRS PVLSWFCSLL LLSTLNVSAL QDLQRGWYTS EDQYYLLLFS 180 TAVCSLHCIS FCLEMCWHPL QAGRPKHCSS LQNCALKTLI YQFLKLTAFC FYHPLFYNGP 240 IMTYKDFSEQ IERPLCKVSA LHVFSGILRL CVWWCLAEFM IHFMYMHAIQ SNETYLEMLP 300 PWAMGGLALA LVQFFYVKYL VLFGAVSLLV RLDGLEPPTL PRCVSIMYSF TGMWRHFDVG 360 LYKWLIRYIY VPLGGSRHGA FRKLLSTALA FGFVCFWHGC HDYLLYWALL NWVGVLVENA 420 FALLFSSPPL RHAIVYCLTP RMQRRGLALI SAFSTAFLIL SNLFFLGGTH VGRIFWKKLF 480 VQDWSSVAVP MVAFLYCFAQ VGIEWDMR 508 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | HHAT | 480017 | A0A5F4DKS6 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | HHAT | 102188788 | A0A452E3S0 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | HHAT | 55733 | Q5VTY9 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Hhat | 226861 | Q8BMT9 | CLP | Mus musculus | Publication | More>> | |
| 1:1 ortholog | HHAT | 469670 | H2Q128 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | HHAT | F1S2U1 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Hhat | M0R7X5 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | hhat | 560334 | F8W2J4 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005783 | endoplasmic reticulum |
| GO:0016021 | integral component of membrane |
| GO:0016409 | palmitoyltransferase activity |
| GO:0016746 | transferase activity, transferring acyl groups |
| GO:0018345 | protein palmitoylation |
| GO:0007224 | smoothened signaling pathway |
| Pfam ID | Pfam Term |
|---|---|
| PF03062 | MBOAT |