| Tag | Content |
|---|---|
| Uniprot ID | F1S2U1 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSSSCP00000016547 |
| Ensembl nucleotide ID | ENSSSCG00000015607 |
| Gene name | Hedgehog acyltransferase |
| Gene symbol | HHAT |
| Organism | Sus scrofa |
| NCBI taxa ID | 9823 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MLPRWELSFY LFASLGFHFY SFYEVFKVSR EHEEELDQEF DLETDSLFGG LKKDPTDFEW 60 SFWMEWGKQR LAWLLLGHVG VSQVANLLAR KHRPWILAAY GMWACHCALG TRGTAMVLLH 120 TTISFCVAQF RSLALSWLCS LFLLSTLRLQ DVEEVKRGWY ETENEYYLLQ FTLTVRCLYY 180 TSFSLELCWQ QLPAERAFYS FPWMVAYVFY YPVFHNGPIL SFPEFLTQMQ PREQGSLKAS 240 FSILVRGLGR LLFYWWLVEL MVHLMYMHAI CSSAPLLSAV SCWTLGGLAL AQVLFFYVKY 300 LVLFGVPALL MRLDGLSPPP LPRCVSTMFS FTGMWRYFDV GLHDFLVRYV YIPVGGSQHG 360 LLGTLFSTAV TFAFVSYWHG GNDYLWCWAA LNWLGVTVES GVRRLVQKPS IQDSLAQVLS 420 PQARRRFHAA LASCSTSMLI LSNLVFLGGN QVGKSTGIGS SFKAGHG 467 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | HHAT | 480017 | A0A5F4DKS6 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | HHAT | 102188788 | A0A452E3S0 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | HHAT | 55733 | Q5VTY9 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Hhat | 226861 | Q8BMT9 | CLP | Mus musculus | Publication | More>> | |
| 1:1 ortholog | HHAT | 469670 | H2Q128 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | HHAT | F1S2U1 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Hhat | M0R7X5 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | hhat | 560334 | F8W2J4 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005783 | endoplasmic reticulum |
| GO:0016021 | integral component of membrane |
| GO:0016409 | palmitoyltransferase activity |
| GO:0016746 | transferase activity, transferring acyl groups |
| GO:0018345 | protein palmitoylation |
| GO:0007224 | smoothened signaling pathway |
| Pfam ID | Pfam Term |
|---|---|
| PF03062 | MBOAT |