| Tag | Content |
|---|---|
| Uniprot ID | M0R7X5 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSRNOP00000065563 |
| Ensembl nucleotide ID | ENSRNOG00000003925 |
| Gene name | Hedgehog acyltransferase |
| Gene symbol | Hhat |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MLSRWELTLC LLVSLGFHFR SFYEVYKVSR EHEEELDQEF ELEMDDSIGG LKKDPTDFEW 60 NFWLEWGKQR LVWLLLGHMA VSQLATLLTK KHRPWIIMIY GMWACWCVLG APGVVMVLLH 120 TTIAFCVAQF RSMLLSWLCS LLLLSTLRLQ SVEEVKRRWY KTESEYYLLQ FTLTVRCLYY 180 TSFSLELCRQ PPSAQRACFS FPWLLTYVFY YPVFHNGPIL NFPEFFRQMQ QPELSSLQHS 240 LCILAKGLGR LLCWWWLAEL MVHLMYMHAL YSSIPLLESV SCWTLGGLAL AQVLFFYVKY 300 LVLFGAPALL MRLDGLTPPP LPRCVSTMFS FTGMWRYFDV GLHNFLIRYV YIPLGGSQHG 360 LLGTLLSTAM TFAFVSYWHG SYEDLWCWAA LNWLGVTVES GVRRLLQTPC VRETLARHLS 420 PQARRRLHAL LASCSTSMLI LFNLVFLEGI QVGKTYWNRI FLQGWPWVTL SVLGFLYCYS 480 HVGIAWAQTY TVL 493 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | HHAT | 480017 | A0A5F4DKS6 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | HHAT | 102188788 | A0A452E3S0 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | HHAT | 55733 | Q5VTY9 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Hhat | 226861 | Q8BMT9 | CLP | Mus musculus | Publication | More>> | |
| 1:1 ortholog | HHAT | 469670 | H2Q128 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | HHAT | F1S2U1 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Hhat | M0R7X5 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | hhat | 560334 | F8W2J4 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005783 | endoplasmic reticulum |
| GO:0016021 | integral component of membrane |
| GO:0016409 | palmitoyltransferase activity |
| GO:0016746 | transferase activity, transferring acyl groups |
| GO:0018345 | protein palmitoylation |
| GO:0007224 | smoothened signaling pathway |
| Pfam ID | Pfam Term |
|---|---|
| PF03062 | MBOAT |