Gene: HHAT

Basic information

Tag Content
Uniprot ID H2Q128; A0A2J8QVL0;
Entrez ID 469670
Genbank protein ID JAA02252.1
Genbank nucleotide ID XM_001169380.3; XM_016938147.1; XM_016938152.1;
Ensembl protein ID ENSPTRP00000003280
Ensembl nucleotide ID ENSPTRG00000001945
Gene name Hedgehog acyltransferase
Gene symbol HHAT
Organism Pan troglodytes
NCBI taxa ID 9598
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MLPQWELALY LLASLGFHFY SFYEVYKVSR EHEEELDQEF ELETDTLFGG LKKDATDFEW 60
SFWMEWGKQW LVWLLLGHMV VSQMATLLAR KHRPWILMLY GMWACWCVLG TPGVAMVLLH 120
TTISFCVAQF RSQLLTWLCS LLLLSTLRLQ GVEEVKRRWY KTENEYYLLQ FTLTVRCLYY 180
TSFSLELCWQ QLPAASTSYS FPWMLAYVFY YPVLHNGPIL SFSEFIKQMQ QQEHDSLKAS 240
LCVLALGLGR LLCWWWLAEL MAHLMYMHAI YSSIPLLETV SCWTLGGLAL AQVLFFYVKY 300
LVLFGVPALL MRLDGLTPPA LPRCVSTMFS FTGMWRYFDV GLHNFLIRYV YIPVGGSQHG 360
LLGTLFSTAM TFAFVSYWHG GYDYLWCWAA LNWLGVTVEN GVWRLVETPC IQDSLARYFS 420
PQARRRFHAA LASCSTSMLI LSNLVFLGGN EVGKTYWNRI FIQGWPWVTL SVLGFLYCYS 480
HVGIAWAQTY ATD 493

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologHHAT480017A0A5F4DKS6Canis lupus familiarisPredictionMore>>
1:1 orthologHHAT102188788A0A452E3S0Capra hircusPredictionMore>>
1:1 orthologHHAT55733Q5VTY9Homo sapiensPredictionMore>>
1:1 orthologHhat226861Q8BMT9CLPMus musculusPublicationMore>>
1:1 orthologHHAT469670H2Q128Pan troglodytesPredictionMore>>
1:1 orthologHHATF1S2U1Sus scrofaPredictionMore>>
1:1 orthologHhatM0R7X5Rattus norvegicusPredictionMore>>
1:1 orthologhhat560334F8W2J4Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0016021 integral component of membrane
GO:0016409 palmitoyltransferase activity
GO:0018345 protein palmitoylation
GO:0007224 smoothened signaling pathway

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0012 Acyltransferase
KW-0472 Membrane
KW-1185 Reference proteome
KW-0808 Transferase
KW-0812 Transmembrane
KW-1133 Transmembrane helix

Interpro

InterPro ID InterPro Term
IPR032981 HHAT
IPR004299 MBOAT_fam

PROSITE

PROSITE ID PROSITE Term

Pfam

Pfam ID Pfam Term
PF03062 MBOAT