| Tag | Content |
|---|---|
| Uniprot ID | A3KN98 |
| Entrez ID | 315644 |
| Genbank protein ID | AAI33726.1 |
| Genbank nucleotide ID | NM_001127712.1 |
| Ensembl protein ID | ENSRNOP00000055965 |
| Ensembl nucleotide ID | ENSRNOG00000038746 |
| Gene name | Bco2 protein |
| Gene symbol | Bco2 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MLGPQQSLPC IAPLLTTVEE TLSTVSARVR GHIPEWLNGY LLRVGPGKFE FGKDRYNHWF 60 DGMALLHQFK MEKGTVTYKS KFLQSDTYKA NSAGDRIVIS EFGTLALPDP CKSIFERFMS 120 RFEPPTMTDN TSVNFVQYKG DYYMSTETNF MNKVDIETLE RTEKVDWSKF VAVNGATAHP 180 HYDPDGTAYN MGNTYGPRGS CYNIIRVPPK KKEPGETIHG AQVVCSIASS EKMKPSYYHS 240 FGMTKNYIVF VEQPLKMKLW KIITSKIRGK SFADGISWEP QYNTRFHVVD KHTGQPLPGV 300 YYSKPFLTYH QINAFEDQGC IVIDLCCEDD GRSLDIYQLQ NLRKAGEELD QVYKAKAKSF 360 PRRFVLPLDI SVGAPEGENL RPLPYSSASV VKQGDREIWC SPENLHQEDL EEEGGIEFPQ 420 INYGRFSGKK YSFFYGCGFR HLVGDSLIKV DVVNKTLRVW REEGCYPSEP VFVPVPGADE 480 EDSGAILSVV ITPNQGESNF LLVLDAKNFT ELGRAEVPVR MPYGFHGTFV PI 532 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | BCO2 | 479437 | E2RS36 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | BCO2 | A0A452E744 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | BCO2 | 83875 | Q9BYV7 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Bco2 | 170752 | Q99NF1 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | BCO2 | 451548 | H2R4A4 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | BCO2 | 100344631 | G1SXN4 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Bco2 | 315644 | A3KN98 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005739 | mitochondrion |
| GO:0003834 | beta-carotene 15,15'-monooxygenase activity |
| GO:0010436 | carotenoid dioxygenase activity |
| GO:0046872 | metal ion binding |
| GO:0016702 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen |
| GO:0004744 | retinal isomerase activity |
| GO:0016121 | carotene catabolic process |
| GO:0016119 | carotene metabolic process |
| GO:0016116 | carotenoid metabolic process |
| GO:0055114 | oxidation-reduction process |
| GO:0051881 | regulation of mitochondrial membrane potential |
| GO:2000377 | regulation of reactive oxygen species metabolic process |
| GO:0042574 | retinal metabolic process |
| GO:0016122 | xanthophyll metabolic process |
| InterPro ID | InterPro Term |
|---|---|
| IPR004294 | Carotenoid_Oase |
| Pfam ID | Pfam Term |
|---|---|
| PF03055 | RPE65 |