| Tag | Content |
|---|---|
| Uniprot ID | G1SXN4 |
| Entrez ID | 100344631 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_008261401.2 |
| Ensembl protein ID | ENSOCUP00000008329 |
| Ensembl nucleotide ID | ENSOCUG00000009662 |
| Gene name | Beta-carotene oxygenase 2 |
| Gene symbol | BCO2 |
| Organism | Oryctolagus cuniculus |
| NCBI taxa ID | 9986 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MFFQIFLGFV SNLSTIAVGF LSVIMHRLSV LKKSMGTVSP HQKEAIVGQR QNLPCIEPLV 60 STVEETPGMV SARVRGHLPE WLNGYLLRIG PGKFEFGKDK YNHWFDGMAL LHQFRMEKGT 120 VTYRSKFLQS DTYKANSVHN RIMISEFGTL ALPDPCKNVF ERFMSKFEPT ATTDNTNVNY 180 VQYKGDYYVS TETNFMNKVD IETLEKTEKV DWSKFIAVNG ATAHPHYDSD GTAYNMGNSY 240 GPRGSCYNVI RVPPEKADVG ETIHGAEVIC SIAPAESTKP SYYHSFGMTR NYIIFIEQPL 300 KMNLWKIVTS KIRGKAISDG ISWEPQYNTR FHVVDKHTGQ LLPEMYYSEP FVTFHQINAF 360 EDQGCIVIDM CCQDNGKSLD VYQLQNLRRA GKGLDQVYNS VARSFPRRFV LPLNVSINAP 420 EGKNLSPLTY SSASAVKQAD GKIWCSHESL HHKDLMEEGG IEFPQINYGK FSGKKYRFFY 480 GCGFRHLVGD SLIKVDVVNK TLKVWRKDGF YPSEPIFVPV PGASEEDGGV VLSVVITPNQ 540 NESNFLLVLD AKNFEELGRA EVPVQIPYGF HGTFIPI 577 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | BCO2 | 479437 | E2RS36 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | BCO2 | A0A452E744 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | BCO2 | 83875 | Q9BYV7 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Bco2 | 170752 | Q99NF1 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | BCO2 | 451548 | H2R4A4 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | BCO2 | 100344631 | G1SXN4 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Bco2 | 315644 | A3KN98 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0016021 | integral component of membrane |
| GO:0046872 | metal ion binding |
| GO:0016702 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen |
| InterPro ID | InterPro Term |
|---|---|
| IPR004294 | Carotenoid_Oase |
| Pfam ID | Pfam Term |
|---|---|
| PF03055 | RPE65 |