| Tag | Content |
|---|---|
| Uniprot ID | A5GFN2 |
| Entrez ID | 492315 |
| Genbank protein ID | CAN13189.1; CAN13248.1; |
| Genbank nucleotide ID | XM_005673044.2 |
| Ensembl protein ID | |
| Ensembl nucleotide ID | |
| Gene name | Bone morphogenetic protein 7 (Osteogenic protein 1) |
| Gene symbol | BMP7 |
| Organism | Sus scrofa |
| NCBI taxa ID | 9823 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MHVRSLRAAA PHSFVALWAP LFLLRSALAD FSLDNEVHSS FIHRRLRSQE RREMQREILS 60 ILGLPHRPRP HLQGKHNSAP MFMLDLYNAM AVEEGGGPDG QGFSYPYKAV FSTQGPPLAS 120 LQDSHFLTDA DMVMSFVNLV EHDKEFFHPR YHHREFRFDL SKIPEGEAVT AAEFRIYKDY 180 IREHFNNETF RISVYQVLQE HLGRDSDLFL LDSRTLWASE EGWLVFDITA TSNHWVVNPR 240 HNLGLQLSVE TLDGQSINPK LAGLIGRQGP QNKQPFMVAF FKATEVHLRS TRSTGGKQRS 300 QNRSKTPKNQ EALRVANVAE NSSSDQRQAC KKHELYVSFR DLGWQDWIIA PEGYAAYYCE 360 GECAFPLNSY MNATNHAIVQ TLVHFINPET VPKPCCAPTQ LNAISVLYFD DSSNVILKKY 420 RNMVVRACGC H 431 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | BMP7 | 540595 | F1MLT0 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | BMP7 | 102177903 | A0A452E223 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | BMP7 | 100050299 | E0A9E2 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | BMP7 | 655 | P18075 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Bmp7 | 12162 | P23359 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | BMP7 | 458357 | H2QKM7 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | BMP7 | 492315 | A5GFN2 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | Bmp7 | 85272 | G3V6W8 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | bmp7b | 557567 | F1QD07 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005615 | extracellular space |
| GO:0070700 | BMP receptor binding |
| GO:0005125 | cytokine activity |
| GO:0008083 | growth factor activity |
| GO:1905069 | allantois development |
| GO:0007411 | axon guidance |
| GO:0030509 | BMP signaling pathway |
| GO:0060445 | branching involved in salivary gland morphogenesis |
| GO:0048754 | branching morphogenesis of an epithelial tube |
| GO:0048738 | cardiac muscle tissue development |
| GO:0060411 | cardiac septum morphogenesis |
| GO:0060710 | chorio-allantoic fusion |
| GO:0048596 | embryonic camera-type eye morphogenesis |
| GO:0030326 | embryonic limb morphogenesis |
| GO:0009880 | embryonic pattern specification |
| GO:0060272 | embryonic skeletal joint morphogenesis |
| GO:0003272 | endocardial cushion formation |
| GO:0030855 | epithelial cell differentiation |
| GO:0061384 | heart trabecula morphogenesis |
| GO:0030902 | hindbrain development |
| GO:0048762 | mesenchymal cell differentiation |
| GO:0001707 | mesoderm formation |
| GO:0072136 | metanephric mesenchymal cell proliferation involved in metanephros development |
| GO:0072133 | metanephric mesenchyme morphogenesis |
| GO:0070487 | monocyte aggregation |
| GO:0072125 | negative regulation of glomerular mesangial cell proliferation |
| GO:0043407 | negative regulation of MAP kinase activity |
| GO:0072040 | negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis |
| GO:0045839 | negative regulation of mitotic nuclear division |
| GO:0045665 | negative regulation of neuron differentiation |
| GO:0045746 | negative regulation of Notch signaling pathway |
| GO:0060686 | negative regulation of prostatic bud formation |
| GO:0045892 | negative regulation of transcription, DNA-templated |
| GO:0072134 | nephrogenic mesenchyme morphogenesis |
| GO:0021502 | neural fold elevation formation |
| GO:0042475 | odontogenesis of dentin-containing tooth |
| GO:0003344 | pericardium morphogenesis |
| GO:0060037 | pharyngeal system development |
| GO:0043065 | positive regulation of apoptotic process |
| GO:0030501 | positive regulation of bone mineralization |
| GO:0090336 | positive regulation of brown fat cell differentiation |
| GO:1905312 | positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis |
| GO:1900006 | positive regulation of dendrite development |
| GO:0010718 | positive regulation of epithelial to mesenchymal transition |
| GO:0034116 | positive regulation of heterotypic cell-cell adhesion |
| GO:1900106 | positive regulation of hyaluranon cable assembly |
| GO:0045669 | positive regulation of osteoblast differentiation |
| GO:0010862 | positive regulation of pathway-restricted SMAD protein phosphorylation |
| GO:0010800 | positive regulation of peptidyl-threonine phosphorylation |
| GO:0045944 | positive regulation of transcription by RNA polymerase II |
| GO:0034504 | protein localization to nucleus |
| GO:0060687 | regulation of branching involved in prostate gland morphogenesis |
| GO:0060395 | SMAD protein signal transduction |
| GO:0043401 | steroid hormone mediated signaling pathway |
| GO:0001657 | ureteric bud development |